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Florence, SC Hotels & Motels | HotelGuides.com
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Hotels > US Hotels > Hotels in South Carolina > Florence Hotels & Motels

Hotels and Motels in Florence, SC



Florence is in east central South Carolina, 80 miles east of downtown Columbia and 65 miles northwest of Myrtle Beach. Most of the hotels in Florence are near I-95. Only one is downtown.

Map of Florence, SC Hotels and Motels
 

Best value hotels are listed first. These are good hotels that cost less than other good hotels. Based on guest reviews and nightly room rates.

  • Howard Johnson Inn Northwest Florence - I-95, Exit 164
    2038 West Lucas Street, I-95, Exit 164, Florence, SC 29501 Call Us

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    Howard Johnson Inn Northwest Florence - I-95, Exit 164

    Rated Average
    • Cheap, smoke-free motel near I-95 at US 52
    • Outdoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 588 reviews 
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  • Red Roof Inn Florence - I-95, Exit 160
    2690 David McLeod Blvd, I-95, Exit 160, Florence, SC 29501 Call Us

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    Dates
    Red Roof Inn Florence - I-95, Exit 160

    Rated Average
    • Cheap, smoke-free motel near I-95
    • Also near Florence Civic Center
    • 2 floors, 112 rooms - no elevator
    • No swimming pool
    • Free WiFi
    • Free parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 470 reviews 
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  • Days Inn I-95 North Florence - I-95, Exit 164
    2111 West Lucas Street, I-95, Exit 164, Florence, SC 29501 Call Us

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    Days Inn I-95 North Florence - I-95, Exit 164

    Rated Average
    • Cheap motel near I-95 at US 52
    • 2 floors, 103 rooms and suites - no elevator
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 972 reviews 
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  • Park Inn by Radisson Florence - I-95, Exit 164
    1729 Mandeville Road, I-95, Exit 164, Florence, SC 27501 Call Us

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    Park Inn by Radisson Florence - I-95, Exit 164

    Rated Average
    • Midscale, smoke-free, interstate hotel near I-95 at US 52
    • 3 floors, 60 rooms - elevator
    • Heated indoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 87 reviews 
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  • Best Western Inn Florence - I-95, Exit 164
    1808 West Lucas Street, I-95, Exit 164, Florence, SC 29501 Call Us

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    Best Western Inn Florence - I-95, Exit 164

    Rated Average
    • Midscale motel near I-95 at US 52
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 550 reviews 
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  • Econo Lodge Florence - I-95, Exit 164
    1920 West Lucas Street, I-95, Exit 164, Florence, SC 29501 Call Us

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    Econo Lodge Florence - I-95, Exit 164

    Rated Average
    • Cheap motel near I-95 at US 52
    • Some smoking rooms
    • Outdoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 251 reviews 
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  • Affordable Suites of America Florence - I-95, Exit 160
    530 Woody Jones Blvd, I-95, Exit 160, Florence, SC 29501 Call Us

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    Affordable Suites of America Florence - I-95, Exit 160

    Rated Very High
    • Budget, smoke-free, all-suite, extended-stay motel
    • Near Florence Center
    • 2 floors, 29 suites - no elevator
    • No swimming pool
    • Kitchen in every suite
    • Free WiFi
    • Free parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 41 reviews 
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  • La Quinta Inn & Suites Florence - I-95, Exit 164
    2123 West Lucas Street, I-95, Exit 164, Florence, SC 29501 Call Us

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    La Quinta Inn & Suites Florence - I-95, Exit 164

    Rated Average
    • Midscale, smoke-free hotel near I-95 at US 52, Exit 164
    • 3 floors, 84 rooms and suites - elevator
    • Outdoor swimming pool open in summer Exercise room
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 1237 reviews 
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  • Quality Inn & Suites Civic Center Florence - I-95, Exit 160
    150 Dunbarton Drive, I-95, Exit 160, Florence, SC 29501 Call Us

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    Quality Inn & Suites Civic Center Florence - I-95, Exit 160

    Rated High
    • Midscale motel near Florence Center
    • Also near I-95, I-20, and Florence Mall
    • 2 floors, 80 rooms and suites - no elevator
    • Some smoking rooms
    • Outdoor swimming pool open in summer Exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 331 reviews 
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  • Country Inn & Suites by Radisson Florence - I-95, Exit 164
    1739 Mandeville Road, I-95, Exit 164, Florence, SC 29501 Call Us

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    Country Inn & Suites by Radisson Florence - I-95, Exit 164

    Rated Average
    • Upper-midscale, smoke-free hotel near I-95 at US 52
    • 3 floors, 80 rooms and suites - elevator
    • Outdoor swimming pool open in summer Exercise room
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 947 reviews 
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  • Comfort Inn & Suites Florence - I-95, Exit 160
    527 Woody Jones Blvd, I-95, Exit 160, Florence, SC 29501 Call Us

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    Comfort Inn & Suites Florence - I-95, Exit 160

    Rated High
    • Midscale, smoke-free hotel near Florence Center
    • Also near I-20 Business, Exit 141
    • 3 floors, 89 rooms and suites - elevator
    • Outdoor swimming pool open in summer Exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - limited truck parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 77 reviews 
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  • Holiday Inn Express & Suites I-95 Florence - I-95, Exit 170
    2101 Florence Harlee Blvd, I-95, Exit 170, Florence, SC 29506 Call Us

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    Holiday Inn Express & Suites I-95 Florence - I-95, Exit 170

    Rated High
    • Upper-midscale, smoke-free hotel near I-95 at SC 327
    • 4 floors, 86 rooms and suites
    • Heated indoor swimming pool - exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 231 reviews 
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  • Holiday Inn Express & Suites Civic Center Florence - I-95, Exit 160
    3440 West Radio Drive, I-95, Exit 160, Florence, SC 29501 Call Us

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    Holiday Inn Express & Suites Civic Center Florence - I-95, Exit 160

    Rated Very High
    • Upper-midscale, smoke-free hotel near I-95 at I-20
    • Also near Florence Center
    • 3 floors, 87 rooms and suites - elevator
    • Heated indoor swimming pool - exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 533 reviews 
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  • Hyatt Place Hotel Downtown Florence
    100 East Evans Street, Florence, SC 29506 Call Us

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    Dates
    Hyatt Place Hotel Downtown Florence

    Rated High
    • Upscale, smoke-free, full-service, downtown hotel
    • 5 floors, 106 rooms and suites
    • Outdoor swimming pool open in summer
    • Exercise room
    • Restaurant - lounge
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 188 reviews 
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  • Courtyard by Marriott Florence - I-95, Exit 160
    2680 Hospitality Blvd, I-95, Exit 160, Florence, SC 29501 Call Us

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    Courtyard by Marriott Florence - I-95, Exit 160

    Rated High
    • Upscale, smoke-free hotel
    • Near Florence Center
    • 3 floors, 90 rooms and suites - elevator
    • Indoor swimming pool - exercise room
    • Restaurant - lounge
    • Restaurant open for breakfast and dinner only
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 560 reviews 
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  • Tru by Hilton Florence - I-95, Exit 164
    2140 West Lucas Street, I-95, Exit 164, Florence, SC 29501 Call Us

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    Dates
    Tru by Hilton Florence - I-95, Exit 164

    Rated Average
    • Midscale, smoke-free hotel near I-95 at US 52
    • 5 floors, 98 rooms
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 232 reviews 
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  • Hilton Garden Inn Florence - I-95, Exit 160
    2671 Hospitality Blvd, I-95, Exit 160, Florence, SC 29501 Call Us

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    Dates
    Hilton Garden Inn Florence - I-95, Exit 160

    Rated Average
    • Upscale, smoke-free hotel near I-95
    • Also near Florence Center
    • 8 floors, 186 rooms and suites
    • Heated indoor swimming pool - exercise room
    • Restaurant - lounge - room service
    • Restaurant open for breakfast and dinner only
    • Microwave and refrigerator in every room
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 1082 reviews 
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  • Comfort Suites Florence - I-95, Exit 164
    2120 West Lucas Street, I-95, Exit 164, Florence, SC 29501 Call Us

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    Dates
    Comfort Suites Florence - I-95, Exit 164

    Rated High
    • Midscale, smoke-free, all-suite hotel
    • Near I-95 at US 52
    • 4 floors, 77 suites
    • Heated indoor swimming pool - exercise room
    • Microwave and refrigerator in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 549 reviews 
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  • SpringHill Suites by Marriott Florence - I-95, Exit 160
    2670 Hospitality Blvd, I-95, Exit 160, Florence, SC 29501 Call Us

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    SpringHill Suites by Marriott Florence - I-95, Exit 160

    Rated Very High
    • Upscale, smoke-free, all-suite hotel near I-95
    • Also near Florence Civic Center
    • 4 floors, 95 suites
    • Heated indoor swimming pool - exercise room
    • Microwave and refrigerator in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 649 reviews 
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  • Fairfield Inn & Suites by Marriott Florence - I-95, Exit 160
    501 Woody Jones Blvd, I-95, Exit 160, Florence, SC 29501 Call Us

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    Dates
    Fairfield Inn & Suites by Marriott Florence - I-95, Exit 160

    Rated High
    • Upper-midscale, smoke-free hotel
    • Near Florence Center
    • 4 floors, 70 rooms, 16 suites
    • Heated indoor swimming pool
    • 24-hour exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 206 reviews 
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  • Hotel Florence
    126 West Evans Street, Florence, SC 29501 Call Us

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    Dates
    Hotel Florence

    Rated Very High
    • Upscale, smoke-free, full-service, downtown hotel
    • 3 miles from Florence Airport
    • A Tapestry Collection by Hilton hotel
    • 3 floors, 64 rooms - elevator
    • No shuttle to Florence Airport
    • No swimming pool
    • Exercise room
    • Restaurant - lounge - room service
    • Free WiFi
    • Free parking
    • Park and fly not allowed
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 604 reviews 
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  • Hampton Inn & Suites Civic Center Florence - I-95, Exit 160
    3000 West Radio Drive, I-95, Exit 160, Florence, SC 29501 Call Us

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    Dates
    Hampton Inn & Suites Civic Center Florence - I-95, Exit 160

    Rated High
    • Upper-midscale, smoke-free hotel
    • Near I-95 and civic center
    • Also near GE and Magnolia Mall
    • 3 floors, 82 rooms and suites - elevator
    • Outdoor swimming pool open all year - exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 674 reviews 
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  • Hampton Inn & Suites Florence - I-95, Exit 164
    1735 Stokes Road, I-95, Exit 164, Florence, SC 29501 Call Us

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    Dates
    Hampton Inn & Suites Florence - I-95, Exit 164

    Rated Average
    • Upper-midscale, smoke-free hotel
    • Near I-95 at US 52, Exit 164
    • 5 floors, 136 rooms and suites
    • Heated indoor swimming pool - exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 1276 reviews 
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  • Residence Inn by Marriott Florence - I-95, Exit 160
    2660 Hospitality Blvd, I-95, Exit 160, Florence, SC 29501 Call Us

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    Dates
    Residence Inn by Marriott Florence - I-95, Exit 160

    Rated High
    • Upscale, smoke-free, all-suite, extended-stay hotel
    • Near Florence Center
    • 4 floors, 94 suites
    • Outdoor swimming pool open all year
    • 24-hour exercise room
    • Kitchen in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 527 reviews 
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  • Microtel Inn & Suites by Wyndham Florence - I-95, Exit 164
    1912 Enterprise Drive, I-95, Exit 164, Florence, SC 29502 Call Us

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    Microtel Inn & Suites by Wyndham Florence - I-95, Exit 164

    Rated Low – Not Recommended
    • Cheap, smoke-free hotel near I-95 at US 52
    • 3 floors; 83 rooms, 19 suites - elevator
    • No swimming pool
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    • Not pet friendly
  • Warning: This hotel overbooked and did not honor a confirmed reservation. - Dec 2022
  • TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 383 reviews 
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  • Clarion Inn & Suites Florence - I-95, Exit 164
    1819 West Lucas Street, Building A, I-95, Exit 164, Florence, SC 29501 Call Us

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    Dates
    Clarion Inn & Suites Florence - I-95, Exit 164

    Rated Low – Not Recommended
    • Upper-midscale, smoke-free motel near I-95 at US 52
    • 2 floors, 76 rooms - no elevator
    • No swimming pool
    • Exercise room
    • Microwave and refrigerator in every room
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 596 reviews 
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  • Baymont Inn & Suites Florence - I-95, Exit 164
    1826 West Lucas Street, I-95, Exit 164, Florence, SC 29501 Call Us

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    Baymont Inn & Suites Florence - I-95, Exit 164

    Rated Low – Not Recommended
    • Midscale, smoke-free motel near I-95 at US 52
    • 2 floors, 116 rooms and suites - no elevator
    • Outdoor swimming pool open in summer Exercise room
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 1966 reviews 
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  • Days Inn Civic Center Florence - I-95, Exit 160
    140 Dunbarton Drive, I-95, Exit 160, Florence, SC 29501 Call Us

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    Dates
    Days Inn Civic Center Florence - I-95, Exit 160

    Rated Low – Not Recommended
    • Cheap, smoke-free motel near Florence Center
    • Also near Magnolia Mall and I-95 at I-20
    • Outdoor swimming pool open in summer
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 731 reviews 
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  • MainStay Suites Florence - I-95, Exit 164
    1819 West Lucas Street, Building B, I-95, Exit 164, Florence, SC 29501 Call Us

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    Dates
    MainStay Suites Florence - I-95, Exit 164

    Rated Very Low – Not Recommended
    • Midscale, smoke-free, all-suite, extended-stay motel
    • Near I-95 at US 52, Exit 164
    • 2 floors, 103 suites - no elevator
    • No swimming pool
    • Exercise room
    • Kitchen in every suite
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  1.0 of 5 stars
    Based on 1 reviews 
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  • Travelodge Florence - I-95, Exit 157
    3783A West Palmetto Street, I-95, Exit 157, Florence, SC 29502 Call Us

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    Travelodge Florence - I-95, Exit 157

    Rated Very Low – Not Recommended
    • Cheap, interstate motel near I-95 at US 76
    • 2 floors, 50 rooms - no elevator
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Microwave and refrigerator in every room
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  2.5 of 5 stars
    Based on 278 reviews 
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More about Florence

We can also help you find hotels in Florence, Kentucky and in Florence, Indiana.

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Florence Info

Pet Friendly Hotels in or near Florence

Florence Group Hotel Rates

Map of Florence SC Hotels

Hotels near Me

Nearby Attractions


Pet Friendly Florence Hotels near I-95   0.0 mile SE
Hotels near Sexton Dental Clinic   0.2 mile west
Hotels near Downtown Florence   0.3 mile NW
Hotels near McLeod Regional Medical Center   0.6 mile NE
Hotels near Florence National Cemetery   1.1 miles SE
Hotels near Florence Airport – FLO   2.3 miles east
Hotels near Highway 52 Florence   2.9 miles NW
Hotels near Magnolia Mall   3.7 miles west
Hotels near Florence Center   4.0 miles west
Hotels near Francis Marion University   7 miles east
Hotels near Darlington Raceway   10 miles NW

Nearby Cities


Darlington SC Hotels   10 miles NW
Timmonsville SC Hotels   11 miles SW
Latta SC Hotels   17 miles NE
Marion SC Hotels   21 miles east
Hartsville SC Hotels   21 miles NW
Lake City SC Hotels   22 miles south
Turbeville SC Hotels   25 miles SW
Dillon SC Hotels   28 miles NE
Mullins SC Hotels   29 miles east
Bennettsville SC Hotels   29 miles north
How Do We Order Hotels?

On place pages like this, we order hotels from lowest cost to highest – except we list low-rated hotels at the bottom of the page.

Most of our competitors order these same hotels in other ways that make them more money.
How Do We Define Motel?

To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.

At hotels, on the other hand, you can enter your room only through a hall inside the building.
Book Group Reservations
Hotel Booking Tips
  1. Beware of non-refundable reservations that could cost you a lot of money if you change or cancel them. +Non-refundable reservations are a gamble that will usually save you less than $10. If you make a $90 non-refundable reservation instead of a $100 refundable booking, you are betting $90 to win $10. Would you do that in Las Vegas?
  2. Don't assume you can cancel a non-refundable reservation without penalty if you notify the hotel weeks or even months in advance. +Often you cannot – because some hotels' profit strategy is to get paid more than once for the same room for the same night.
  3. Always read cancellation policies carefully before you make a reservation. + When is the latest date and time you can cancel without penalty?
    More >
  4. When you make a reservation, you will receive a confirmation email. Take a copy with you to the hotel.
  5. The earlier in the afternoon you check into a hotel, the more likely you will get a room or suite that matches your preferences.



Florence Hotels, Motels, Lodging, and Accommodations – Florence, South Carolina SC, USA

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