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  • Red Roof Inn Florence - I-95, Exit 160A

    2690 David McLeod Blvd, I-95, Exit 160A, Florence, SC 29501

    Enter Dates
    Red Roof Inn Florence - I-95, Exit 160A

    Check In15 00
    Check Out11 00

    Rated Average
    • Cheap, smoke-free motel near I-95
    • Also near Florence Civic Center
    • 2 floors, 112 rooms - no elevator
    • No swimming pool
    • Free WiFi
    • Free parking
  • Pet friendly motel - allows pets up to 80 pounds, 1 pet per room - no pet fee. - Dec 2021
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 470 reviews  Read Recent Reviews

  • Clarion Inn & Suites Florence - I-95, Exit 164

    1819 West Lucas Street, Building A, I-95, Exit 164, Florence, SC 29501

    Enter Dates
    Clarion Inn & Suites Florence - I-95, Exit 164

    Check In15 00
    Check Out11 00

    Rated Average
    • Upper-midscale, smoke-free motel near I-95 at US 52
    • 2 floors, 76 rooms - no elevator
    • Outdoor swimming pool is closed until April 2023
    • Exercise room
    • Microwave and refrigerator in every room
    • Free WiFi
    • Free parking - truck parking
  • Pet friendly motel - $25 per night fee for each pet. - Nov 2021
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 596 reviews  Read Recent Reviews

  • Days Inn I-95 North Florence - I-95, Exit 164

    2111 West Lucas Street, I-95, Exit 164, Florence, SC 29501

    Enter Dates
    Days Inn I-95 North Florence - I-95, Exit 164

    Check In15 00
    Check Out11 00

    Rated Average
    • Cheap motel near I-95 at US 52
    • 2 floors, 103 rooms and suites - no elevator
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
  • Pet friendly motel - $10 per night fee for each pet. - Mar 2021
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 972 reviews  Read Recent Reviews

  • Affordable Suites of America Florence - I-95, Exit 160

    530 Woody Jones Blvd, I-95, Exit 160, Florence, SC 29501

    Enter Dates
    Affordable Suites of America Florence - I-95, Exit 160

    Check In1500
    Check Out1100

    Rated Very High
    • Budget, smoke-free, all-suite, extended-stay motel
    • Near Florence Center
    • 2 floors, 29 suites - no elevator
    • No swimming pool
    • Kitchen in every suite
    • Free WiFi
    • Free parking
  • Pet friendly motel - allows up to medium-sized dogs in some suites only, 1 dog per suite - $25 per night pet fee - $250 maximum per stay pet fee. - Sep 2021
  • TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 41 reviews  Read Recent Reviews

  • Best Western Inn Florence - I-95, Exit 164

    1808 West Lucas Street, I-95, Exit 164, Florence, SC 29501

    Enter Dates
    Best Western Inn Florence - I-95, Exit 164

    Check In1500
    Check Out1100

    Rated Average
    • Midscale motel near I-95 at US 52
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
  • Pet friendly motel - allows pets up to 80 pounds, 2 pets per room - $20 per stay pet fee. - Jul 2021
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 550 reviews  Read Recent Reviews

  • Econo Lodge Florence - I-95, Exit 164

    1920 West Lucas Street, I-95, Exit 164, Florence, SC 29501

    Enter Dates
    Econo Lodge Florence - I-95, Exit 164

    Check In14 00
    Check Out11 00

    Rated Average
    • Cheap motel near I-95 at US 52
    • Some smoking rooms
    • Outdoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
  • Pet friendly motel - allows pets up to 40 pounds in 1st floor rooms - $15 per night fee for each pet. - Jan 2022
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 251 reviews  Read Recent Reviews

  • La Quinta Inn & Suites Florence - I-95, Exit 164

    2123 West Lucas Street, I-95, Exit 164, Florence, SC 29501

    Enter Dates
    La Quinta Inn & Suites Florence - I-95, Exit 164

    Check In15 00
    Check Out11 00

    Rated Average
    • Midscale, smoke-free hotel near I-95 at US 52, Exit 164
    • 3 floors, 84 rooms and suites - elevator
    • Outdoor swimming pool open in summer - exercise room
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
  • Pet friendly hotel - allows up to 3 pets per room - $10 per night fee for each pet. - Jul 2021
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 1237 reviews  Read Recent Reviews

  • Quality Inn & Suites Civic Center Florence - I-95, Exit 160

    150 Dunbarton Drive, I-95, Exit 160, Florence, SC 29501

    Enter Dates
    Quality Inn & Suites Civic Center Florence - I-95, Exit 160

    Check In15 00
    Check Out11 00

    Rated Average
    • Midscale motel near Florence Center
    • Also near I-95, I-20, and Florence Mall
    • 2 floors, 80 rooms and suites - no elevator
    • Some smoking rooms
    • Outdoor swimming pool open in summer - exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
  • Pet friendly motel - allows up to 2 pets per room - $20 per stay pet fee. - Jun 2019
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 331 reviews  Read Recent Reviews

  • Country Inn & Suites by Radisson Florence - I-95, Exit 164

    1739 Mandeville Road, I-95, Exit 164, Florence, SC 29501

    Enter Dates
    Country Inn & Suites by Radisson Florence - I-95, Exit 164

    Check In15 00
    Check Out12 00

    Rated Average
    • Upper-midscale, smoke-free hotel near I-95 at US 52
    • 3 floors, 80 rooms and suites - elevator
    • Outdoor swimming pool open in summer - exercise room
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking
  • Pet friendly hotel - allows up to 3 pets per room - $35 per stay pet fee. - Aug 2021
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 947 reviews  Read Recent Reviews

  • Comfort Inn & Suites Florence - I-95, Exit 160

    527 Woody Jones Blvd, I-95, Exit 160, Florence, SC 29501

    Enter Dates
    Comfort Inn & Suites Florence - I-95, Exit 160

    Check In16 00
    Check Out11 00

    Rated High
    • Midscale, smoke-free hotel near Florence Center
    • Also near I-20 Business, Exit 141
    • 3 floors, 89 rooms and suites - elevator
    • Outdoor swimming pool open in summer - exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - limited truck parking
  • Pet friendly hotel - allows pets up to 50 pounds in 1st floor rooms only, 2 pets per room - $50 per stay pet fee. - Oct 2019
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 77 reviews  Read Recent Reviews

  • Hyatt Place Hotel Downtown Florence

    100 East Evans Street, Florence, SC 29506

    Enter Dates
    Hyatt Place Hotel Downtown Florence

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upscale, smoke-free, full-service, downtown hotel
    • Near I-95
    • 5 floors, 106 rooms and suites
    • Outdoor swimming pool open in summer
    • Exercise room
    • Restaurant - lounge
    • Free WiFi
    • Free parking
  • Pet friendly hotel - allows pets up to 80 pounds - $75 per stay pet fee. - Oct 2021
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 188 reviews  Read Recent Reviews

  • Hilton Garden Inn Florence - I-95, Exit 160

    2671 Hospitality Blvd, I-95, Exit 160, Florence, SC 29501

    Enter Dates
    Hilton Garden Inn Florence - I-95, Exit 160

    Check In15 00
    Check Out12 00

    Rated Average
    • Upscale, smoke-free hotel near I-95
    • Also near Florence Center
    • 8 floors, 186 rooms and suites
    • Heated indoor swimming pool - exercise room
    • Restaurant - lounge - room service
    • Restaurant open for breakfast and dinner only
    • Microwave and refrigerator in every room
    • Free WiFi
    • Free parking
  • Pet friendly hotel - allows pets up to 80 pounds - $50 per night fee for each pet. - Aug 2022
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 1082 reviews  Read Recent Reviews

  • Comfort Suites Florence - I-95, Exit 164

    2120 West Lucas Street, I-95, Exit 164, Florence, SC 29501

    Enter Dates
    Comfort Suites Florence - I-95, Exit 164

    Check In15 00
    Check Out11 00

    Rated High
    • Midscale, smoke-free, all-suite hotel
    • Near I-95 at US 52
    • 4 floors, 77 suites
    • Heated indoor swimming pool - exercise room
    • Microwave and refrigerator in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
  • Pet friendly hotel - allows pets up to 20 pounds only, 1 pet per suite - $50 per stay pet fee. - Jun 2021
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 549 reviews  Read Recent Reviews

  • TownePlace Suites by Marriott Florence - I-95, Exit 160

    2650 Hospitality Blvd, I-95, Exit 160, Florence, SC 29501

    Enter Dates
    TownePlace Suites by Marriott Florence - I-95, Exit 160

    Check In1600
    Check Out1100

    Rated Very High
    • Midscale, smoke-free, all-suite, extended-stay hotel
    • Near Florence Center and I-95 at I-20
    • 4 floors, 89 suites
    • Outdoor swimming pool - exercise room
    • Kitchen in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
  • Pet friendly hotel - allows pets up to 50 pounds, 2 pets per suite - $75 per stay pet fee. - Jun 2022
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 257 reviews  Read Recent Reviews

  • Residence Inn by Marriott Florence - I-95, Exit 160

    2660 Hospitality Blvd, I-95, Exit 160, Florence, SC 29501

    Enter Dates
    Residence Inn by Marriott Florence - I-95, Exit 160

    Check In1600
    Check Out1100

    Rated High
    • Upscale, smoke-free, all-suite, extended-stay hotel
    • Near Florence Center
    • 4 floors, 94 suites
    • Outdoor swimming pool open all year
    • 24-hour exercise room
    • Kitchen in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
  • Pet friendly hotel - allows up to 2 pets per suite - $75 per stay pet fee. - Jul 2022
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 527 reviews  Read Recent Reviews

  • Home2 Suites by Hilton Florence - I-95, Exit 160

    900 Woody Jones Blvd, I-95, Exit 160, Florence, SC 29501

    Enter Dates
    Home2 Suites by Hilton Florence - I-95, Exit 160

    Check In15 00
    Check Out11 00

    Rated High
    • Upper-midscale, smoke-free, extended-stay hotel
    • Near Florence Center
    • 5 floors, 83 studio and 1-bedroom suites
    • Indoor swimming pool - exercise room
    • Kitchen in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
  • Pet friendly hotel - allows pets up to 70 pounds, 2 pets per suite - $50 per stay pet fee. - Dec 2021
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 862 reviews  Read Recent Reviews

  • Staybridge Suites Civic Center Florence - I-95, Exit 160

    150 Westpark Drive, I-95, Exit 160, Florence, SC 29501

    Enter Dates
    Staybridge Suites Civic Center Florence - I-95, Exit 160

    Check In16 00
    Check Out12 00

    Rated Very High
    • Upscale, smoke-free, all-suite, extended-stay hotel
    • Near Florence Center
    • 8 floors, 112 studio to 2-bedroom suites
    • Outdoor swimming pool - 24-hour exercise room
    • Kitchen in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
  • Pet friendly hotel - allows pets up to 80 pounds, 2 pets per room - $150 pet fee if staying 7 nights or more - $75 pet fee if staying fewer than 7 nights. - Jun 2018
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 139 reviews  Read Recent Reviews

  • Baymont Inn & Suites Florence - I-95, Exit 164

    1826 West Lucas Street, I-95, Exit 164, Florence, SC 29501

    Enter Dates
    Baymont Inn & Suites Florence - I-95, Exit 164

    Check In15 00
    Check Out11 00

    Rated Low – Not Recommended
    • Midscale, smoke-free motel near I-95 at US 52
    • 2 floors, 116 rooms and suites - no elevator
    • Outdoor swimming pool open in summer - exercise room
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking
  • Pet friendly motel - allows pets in designated pet rooms - $15 per stay fee for each pet. - Aug 2021
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 1966 reviews  Read Recent Reviews

  • Days Inn Civic Center Florence - I-95, Exit 160

    140 Dunbarton Drive, I-95, Exit 160, Florence, SC 29501

    Enter Dates
    Days Inn Civic Center Florence - I-95, Exit 160

    Check In1500
    Check Out1100

    Rated Low – Not Recommended
    • Cheap, smoke-free motel near Florence Center
    • Also near Magnolia Mall and I-95 at I-20
    • Outdoor swimming pool open in summer
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
  • Pet friendly motel - allows pets in designated pet rooms only - $35 per stay pet fee. - Mar 2021
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 731 reviews  Read Recent Reviews

  • Travelodge Florence - I-95, Exit 157

    3783A West Palmetto Street, I-95, Exit 157, Florence, SC 29502

    Enter Dates
    Travelodge Florence - I-95, Exit 157

    Check In14 00
    Check Out11 00

    Rated Very Low – Not Recommended
    • Cheap, interstate motel near I-95 at US 76
    • 2 floors, 50 rooms - no elevator
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Microwave and refrigerator in every room
    • Free WiFi
    • Free parking - truck parking
  • Pet friendly motel - $10 per night pet fee. - Mar 2022
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  2.5 of 5 stars
    Based on 278 reviews  Read Recent Reviews

  • Super 8 Motel Florence - I-95, Exit 164

    1832 1/2 West Lucas Street, I-95, Exit 164, Florence, SC 29501

    Enter Dates
    Super 8 Motel Florence - I-95, Exit 164

    Check In14 00
    Check Out11 00

    Rated Low – Not Recommended
    • Cheap motel near I-95 at US 52
    • 2 floors, 67 rooms - no elevator
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Free continental breakfast
    • Free WiFi
    • Free parking
  • Pet friendly motel - allows up to 3 pets per room - $10 per night fee for each pet. - Aug 2021
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 440 reviews  Read Recent Reviews

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  2. Don't assume you can cancel a non-refundable reservation without penalty if you notify the hotel weeks or even months in advance. +Often you cannot – because some hotels' profit strategy is to get paid more than once for the same room for the same night.
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