Hotels near US 60 at US 421 in Lexington, KY | HotelGuides.com
Our Customers Have Booked Almost 5,000,000 Hotel Reservations
     
Check Rates for Hotels near US 60 at US 421
 Pet Friendly Only 10+ Rooms
Kids Free

HotelGuides.com > Kentucky > Lexington > Hotels & Motels near US 60 at US 421

Hotels near US 60 at US 421 – Lexington, KY


The hotels below are listed in order of their exit number.

If you need help finding a hotel that is open, call us at 1-800-916-4526.
Map of Hotels and Motels near US 60 at US 421
 

Hotels closest to US 60 at US 421

Rates shown below are averages. Click See Rates to see rates for your dates.
  • 0.2 mile Holiday Inn Express Northwest Lexington

    1780 Sharkey Way, Lexington, KY 40511
    0.2 mile from US 60 at US 421

    Enter Dates
    Holiday Inn Express Northwest Lexington

    Check In15 00
    Check Out11 00

    Rated Very High
    • Midscale, smoke-free hotel near US 60 at US 421
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    Not pet friendly - no pets allowed. - Jun 2016
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 373 reviews  Read Recent Reviews

  • 0.3 mile Staybridge Suites Lexington

    125 Louie Place, Lexington, KY 40511
    0.3 mile from US 60 at US 421

    Enter Dates
    Staybridge Suites Lexington

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upscale, smoke-free, all-suite, extended-stay hotel
    • 2 miles from downtown Lexington - near KY 4 at US 421
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 172 reviews  Read Recent Reviews

  • 1.9 miles Candlewood Suites Lexington

    603 Adcolor Drive, Lexington, KY 40511
    1.9 miles from US 60 at US 421

    Enter Dates
    Candlewood Suites Lexington

    Check In15 00
    Check Out12 00

    Rated Very High
    • Midscale, all-suite, extended-stay hotel
    • In north Lexington near KY 922
    • Heated indoor swimming pool - exercise room
    • Free WiFi
    • Free parking - truck parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 261 reviews  Read Recent Reviews

  • 2.0 miles Residence Inn by Marriott North Lexington

    1080 Newtown Pike, Lexington, KY 40511
    2.0 miles from US 60 at US 421

    Enter Dates
    Residence Inn by Marriott North Lexington

    Check In1500
    Check Out1200

    Rated High
    • Upscale, smoke-free, all-suite, extended-stay hotel
    • In north Lexington near KY 922
    • Outdoor swimming pool open in summer
    • Exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 159 reviews  Read Recent Reviews

  • 2.1 miles Courtyard by Marriott Hotel North Lexington

    775 Newtown Court, Lexington, KY 40511
    2.1 miles from US 60 at US 421

    Enter Dates
    Courtyard by Marriott Hotel North Lexington

    Check In1500
    Check Out1200

    Rated High
    • Upscale, smoke-free, north Lexington hotel
    • Near KY 922
    • Heated indoor swimming pool - exercise room
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Feb 2015
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 263 reviews  Read Recent Reviews

  • 2.2 miles Hyatt Regency Hotel Lexington

    401 West High Street, Lexington, KY 40507
    2.2 miles from US 60 at US 421

    Enter Dates
    Hyatt Regency Hotel Lexington

    Check In16 00
    Check Out11 00

    Rated High
    • Upper-upscale, smoke-free, full-service, downtown hotel
    • Connected to Lexington Convention Center
    • Free 24-hour shuttle to Lexington Airport
    • Heated indoor swimming pool - 24-hour exercise room
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jun 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 1546 reviews  Read Recent Reviews

  • 2.3 miles Hilton Hotel Downtown Lexington

    369 West Vine Street, Lexington, KY 40507
    2.3 miles from US 60 at US 421

    Enter Dates
    Hilton Hotel Downtown Lexington

    Check In16 00
    Check Out12 00

    Rated High
    • Upscale, smoke-free, full-service, downtown hotel
    • 2 blocks from Lexington Convention Center
    • Free shuttle to Lexington Airport
    • Heated indoor swimming pool - exercise room
    • Free WiFi
    • Parking costs $10 per night
    Not pet friendly - no pets allowed. - Jan 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 1685 reviews  Read Recent Reviews

  • 2.3 miles SpringHill Suites by Marriott Downtown Lexington

    863 South Broadway, Lexington, KY 40508
    2.3 miles from US 60 at US 421

    Enter Dates
    SpringHill Suites by Marriott Downtown Lexington

    Check In1500
    Check Out1200

    Rated High
    • Midscale, smoke-free, all-suite, downtown hotel
    • Near University of Kentucky
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    Not pet friendly - no pets allowed. - Jul 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 339 reviews  Read Recent Reviews

  • 2.4 miles 21c Museum Hotel Lexington

    167 West Main Street, Lexington, KY 40507
    2.4 miles from US 60 at US 421

    Enter Dates
    21c Museum Hotel Lexington

    Check In1600
    Check Out1100

    Rated Very High
    • Luxury, smoke-free, full-service, boutique hotel
    • Near University of Kentucky
    • No swimming pool
    • 24-hour exercise room
    • Free WiFi
    • Valet parking only - $23 per night
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 1051 reviews  Read Recent Reviews

  • 2.4 miles Marriott City Center Hotel Lexington

    121 West Vine Street, Lexington, KY 40507
    2.4 miles from US 60 at US 421

    Enter Dates
    Marriott City Center Hotel Lexington

    Check In1500
    Check Out1200

    Rated Very High
    • Upscale, smoke-free, full-service, downtown hotel
    • Outdoor rooftop swimming pool - exercise room
    • Free WiFi
    • Parking costs $12 per night
    Not pet friendly - no pets allowed. - Feb 2020
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 17 reviews  Read Recent Reviews

  • 2.5 miles Residence Inn by Marriott City Center Lexington

    150 West Main Street, Lexington, KY 40507
    2.5 miles from US 60 at US 421

    Enter Dates
    Residence Inn by Marriott City Center Lexington

    Check In1500
    Check Out1200

    Rated Very High
    • Upscale, smoke-free, all-suite, extended-stay hotel
    • 7 miles from Lexington Airport
    • Free shuttle to Lexington Airport
    • Outdoor swimming pool open in summer - exercise room
    • Free hot breakfast buffet
    • WiFi costs $13 per night
    • Parking costs $12 per night
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 4 reviews  Read Recent Reviews

  • 2.5 miles Campbell House Hotel Lexington

    1375 South Broadway, Lexington, KY 40504
    2.5 miles from US 60 at US 421

    Enter Dates
    Campbell House Hotel Lexington

    Check In15 00
    Check Out11 00

    Rated Average
    • Upper-upscale, smoke-free, full-service, downtown hotel
    • A Curio Collection by Hilton hotel
    • Free shuttle to Lexington Airport
    • Heated indoor swimming pool - exercise room
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 1107 reviews  Read Recent Reviews

  • 2.5 miles Holiday Inn Express Hotel & Suites Downtown Lexington

    1000 Export Street, Lexington, KY 40504
    2.5 miles from US 60 at US 421

    Enter Dates
    Holiday Inn Express Hotel & Suites Downtown Lexington

    Check In15 00
    Check Out11 00

    Rated High
    • Midscale, smoke-free, downtown hotel
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jun 2019
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 258 reviews  Read Recent Reviews

  • 2.5 miles Sire Hotel Lexington

    120 West 2nd Street, Lexington, KY 40507
    2.5 miles from US 60 at US 421

    Enter Dates
    Sire Hotel Lexington

    Check In16 00
    Check Out11 00

    Rated Very High
    • Upscale, smoke-free, full-service, downtown hotel
    • In Martin Luther King District
    • A Tapestry Collection by Hilton hotel
    • No swimming pool
    • Exercise room
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jan 2018
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 90 reviews  Read Recent Reviews

  • 2.8 miles Embassy Suites Lexington

    1801 Newtown Pike, I-64, Exit 115, Lexington, KY 40511
    2.8 miles from US 60 at US 421

    Enter Dates
    Embassy Suites Lexington

    Check In15 00
    Check Out11 00

    Rated High
    • Upper-upscale, smoke-free, all-suite, full-service hotel
    • In north Lexington near I-64 at KY 922
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Sep 2015
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 1505 reviews  Read Recent Reviews

  • 3.0 miles Marriott Griffin Gate Resort Lexington

    1800 Newtown Pike, I-64, Exit 115, Lexington, KY 40511
    3.0 miles from US 60 at US 421

    Enter Dates
    Marriott Griffin Gate Resort Lexington

    Check In1600
    Check Out1200

    Rated High
    • Upscale, smoke-free, full-service, golf resort
    • In north Lexington near KY 922 and I-64
    • Drop-off shuttle to local attractions costs $100 per person
    • Heated indoor swimming pool - outdoor pool
    • Exercise room
    • Golf course - full-service spa
    • Internet access costs $7 per night
    • Free parking
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 916 reviews  Read Recent Reviews

  • 3.1 miles Clarion Hotel Conference Center Lexington

    1950 Newtown Pike, I-64, Exit 115, Lexington, KY 40511
    3.1 miles from US 60 at US 421

    Enter Dates
    Clarion Hotel Conference Center Lexington

    Check In16 00
    Check Out11 00

    Rated Average
    • Upper-midscale, full-service hotel
    • In north Lexington near I-64
    • Free 24-hour shuttle to Lexington Airport
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 854 reviews  Read Recent Reviews

  • 3.4 miles Quality Inn North Lexington

    1938 Stanton Way, I-64, Exit 115, Lexington, KY 40511
    3.4 miles from US 60 at US 421

    Enter Dates
    Quality Inn North Lexington

    Check In15 00
    Check Out12 00

    Rated Average
    • Midscale, smoke-free, full-service hotel
    • In north Lexington near I-64 at KY 922
    • Free shuttle to Lexington Airport
    • Heated indoor-outdoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 199 reviews  Read Recent Reviews

  • 3.4 miles Fairfield Inn & Suites by Marriott North Lexington

    2100 Hackney Place, I-64, Exit 115, Lexington, KY 40511
    3.4 miles from US 60 at US 421

    Enter Dates
    Fairfield Inn & Suites by Marriott North Lexington

    Check In1500
    Check Out1200

    Rated High
    • Upper-midscale, smoke-free, north Lexington hotel
    • Located near I-64 at KY 922
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 418 reviews  Read Recent Reviews

  • 3.4 miles GLo Best Western Lexington Hotel

    1935 Stanton Way, I-64, Exit 115, Lexington, KY 40511
    3.4 miles from US 60 at US 421

    Enter Dates
    GLo Best Western Lexington Hotel

    Check In1500
    Check Out1100

    Rated Very High
    • Upper-midscale, smoke-free hotel near I-64
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 150 reviews  Read Recent Reviews

  • 3.5 miles La Quinta Inn Lexington

    1920 Stanton Way, Lexington, KY 40511
    3.5 miles from US 60 at US 421

    Enter Dates
    La Quinta Inn Lexington

    Check In15 00
    Check Out12 00

    Rated Average
    • Midscale, north Lexington hotel near KY 922
    • Outdoor swimming pool open in summer
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 565 reviews  Read Recent Reviews

  • 3.8 miles Days Inn Lexington

    1987 North Broadway, I-64, Exit 113, Lexington, KY 40505
    3.8 miles from US 60 at US 421

    Enter Dates
    Days Inn Lexington

    Check In1500
    Check Out1100

    Rated Low – Not Recommended
    • Cheap, full-service, interstate motel
    • Near Thoroughbred Center
    • Also near I-64
    • Some smoking rooms
    • Outdoor swimming pool open in summer - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  2.5 of 5 stars
    Based on 920 reviews  Read Recent Reviews

  • 3.9 miles Residence Inn by Marriott Lexington

    3110 Wall Street, Lexington, KY 40513
    3.9 miles from US 60 at US 421

    Enter Dates
    Residence Inn by Marriott Lexington

    Check In1600
    Check Out1200

    Rated Very High
    • Upscale, smoke-free, all-suite, extended-stay hotel
    • Near Beaumont Centre
    • Free shuttle to Lexington Airport
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 348 reviews  Read Recent Reviews

  • 3.9 miles TownePlace Suites by Marriott Airport Lexington

    980 Midnight Pass, Lexington, KY 40513
    3.9 miles from US 60 at US 421

    Enter Dates
    TownePlace Suites by Marriott Airport Lexington

    Check In1500
    Check Out1200

    Rated Very High
    • Midscale, smoke-free, all-suite, extended-stay hotel
    • Near Beaumont Centre
    • Indoor swimming pool - 24-hour exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 47 reviews  Read Recent Reviews

  • 3.9 miles Courtyard by Marriott Hotel Keenland Lexington

    3100 Wall Street, Lexington, KY 40513
    3.9 miles from US 60 at US 421

    Enter Dates
    Courtyard by Marriott Hotel Keenland Lexington

    Check In1500
    Check Out1200

    Rated High
    • Upscale, smoke-free, highway hotel
    • Near Beaumont Centre
    • Free shuttle to Lexington Airport
    • Heated indoor swimming pool - exercise room
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Feb 2015
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 209 reviews  Read Recent Reviews

  • 4.0 miles Fairfield Inn & Suites by Marriott Lexington

    3050 Lakecrest Circle, Lexington, KY 40513
    4.0 miles from US 60 at US 421

    Enter Dates
    Fairfield Inn & Suites by Marriott Lexington

    Check In1500
    Check Out1200

    Rated High
    • Upper-midscale, smoke-free hotel near Beaumont Centre
    • Free shuttle to Lexington Airport
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - May 2019
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 86 reviews  Read Recent Reviews

  • 4.1 miles Hampton Inn Medical Center Lexington

    1953 Nicholasville Road, Lexington, KY 40503
    4.1 miles from US 60 at US 421

    Enter Dates
    Hampton Inn Medical Center Lexington

    Check In15 00
    Check Out12 00

    Rated Very High
    • Upper-midscale, smoke-free hotel near Fayette Mall
    • Free shuttle to Lexington Airport
    • Outdoor swimming pool open in summer - 24-hour exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jun 2019
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 472 reviews  Read Recent Reviews

  • 4.1 miles Hampton Inn South Lexington

    3060 Lake Crest Circle, Lexington, KY 40513
    4.1 miles from US 60 at US 421

    Enter Dates
    Hampton Inn South Lexington

    Check In15 00
    Check Out11 00

    Rated High
    • Upper-midscale, smoke-free hotel near Beaumont Centre
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    Not pet friendly - no pets allowed. - Jun 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 461 reviews  Read Recent Reviews

  • 4.2 miles Ramada Inn & Conference Center Lexington

    2143 North Broadway, I-64, Exit 113, Lexington, KY 40505
    4.2 miles from US 60 at US 421

    Enter Dates
    Ramada Inn & Conference Center Lexington

    Check In1500
    Check Out1200

    Rated Low – Not Recommended
    • Midscale, smoke-free hotel near Thoroughbred Center
    • Also near I-64
    • Free shuttle to Lexington Airport
    • Heated indoor swimming pool - outdoor pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free park and fly up to 7 nights only
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 1346 reviews  Read Recent Reviews

  • 4.7 miles Home2 Suites by Hilton Medical Center Lexington

    126 East Lowry Lane, Lexington, KY 40515
    4.7 miles from US 60 at US 421

    Enter Dates
    Home2 Suites by Hilton Medical Center Lexington

    Check In15 00
    Check Out12 00

    Rated Very High
    • Midscale, smoke-free, all-suite hotel near Fayette Mall
    • Indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 807 reviews  Read Recent Reviews

  • Why Book Here?
    • We add no fees.
    • Lowest price guarantee
    • Pay at hotel in most cases
    • If you don't like your hotel,
      we'll refund your money.
    • Cash rewards + hotel points too
  • See more reasons
Hotel Guides is Made in USA
Lexington Info

Lexington Hotels and Reviews

Pet-Friendly Lexington Hotels

Lexington Group Hotel Rates



Nearby Attractions


Hotels near Manchester Music Hall   1.7 miles SE
Hotels near Rupp Arena   2.2 miles SE
Hotels near Lexington Convention Center   2.2 miles SE
Hotels near Lexington Opera House   2.2 miles SE
Hotels near Masterson Station Park   2.3 miles NW
Hotels near Transylvania University   2.4 miles SE
Hotels near Downtown Lexington   2.5 miles SE
Hotels near Good Samaritan Hospital Lexington   2.6 miles SE
Hotels near Saint Joseph Hospital Lexington   2.7 miles south
Hotels near University of Kentucky College of Law   2.7 miles SE
Hotels near Memorial Coliseum   2.7 miles SE
Hotels near Singletary Center   2.8 miles SE
Hotels near Federal Medical Center Lexington   2.9 miles NW
Hotels near Whitaker Bank Ballpark   2.9 miles east
Hotels near Shriners Hospital Lexington   3.0 miles SE

Earn Cash Rewards plus Hotel Reward Points

How Do We Order Hotels?

We order the hotels on this page by how close they are to this attraction.

Most of our competitors order these same hotels in other ways that make them more money.
How Do We Define Motel?

To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.

At hotels, on the other hand, you can enter your room only through a hall inside the building.
Lexington Hotel Tips

Important Hotel Tips



Lexington Hotels near Me

Hotels, Motels, Lodging, and Accommodations near US 60 at US 421 – Lexington, Kentucky KY, USA

© 2020 HotelGuides.com, Inc. All rights reserved.

About Us | Terms of Use | Privacy Policy | Security | Contact Us



Home - HotelGuides.com US Hotels Canada Hotels Hotels in other countries View, change, or cancel my reservations Customer Service Our Better Business Bureau rating is A+ Hotel Guides is Made in USA
Hotel Guides

Just a moment while we find

the best deals at the best hotels.