Hotels near US 60 at US 421 in Lexington, KY | HotelGuides.com
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Hotel Guides > Kentucky > Lexington > Hotels & Motels near US 60 at US 421

Hotels near US 60 at US 421 – Lexington, KY


The hotels below are listed in order of their exit number.

Map of Hotels near US 60 at US 421
 

    Hotels closest to US 60 at US 421

    Rates shown below are averages. Click See Rates to see rates for your dates.
  • 0.2 mile Holiday Inn Express Northwest Lexington
    1780 Sharkey Way, Lexington, KY 40511
    0.2 mile from US 60 at US 421
    From $126
    Enter Dates
    Holiday Inn Express Northwest Lexington

    Check In15 00
    Check Out11 00

    Rated Very High
  • Midscale, smoke-free hotel near US 60 at US 421
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking - truck parking
  • Not pet friendly - no pets allowed.
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 370 reviews  Read Recent Reviews

  • 0.3 mile Staybridge Suites Lexington
    125 Louie Place, Lexington, KY 40511
    0.3 mile from US 60 at US 421
    From $105
    Enter Dates
    Staybridge Suites Lexington

    Check In15 00
    Check Out11 00

    Rated Very High
  • Upscale, smoke-free, all-suite, extended-stay hotel
  • 2 miles from downtown Lexington - near KY 4 at US 421
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 166 reviews  Read Recent Reviews

  • 1.9 miles Candlewood Suites Lexington
    603 Adcolor Drive, Lexington, KY 40511
    1.9 miles from US 60 at US 421
    From $76
    Enter Dates
    Candlewood Suites Lexington

    Check In15 00
    Check Out12 00

    Rated Very High
  • Midscale, all-suite, extended-stay hotel
  • In north Lexington near KY 922
  • Heated indoor swimming pool - exercise room
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 258 reviews  Read Recent Reviews

  • 2.0 miles Residence Inn by Marriott North Lexington
    1080 Newtown Pike, Lexington, KY 40511
    2.0 miles from US 60 at US 421
    From $85
    Enter Dates
    Residence Inn by Marriott North Lexington

    Check In1500
    Check Out1200

    Rated High
  • Upscale, smoke-free, all-suite, extended-stay hotel
  • In north Lexington near KY 922
  • Outdoor swimming pool open in summer
  • Exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 154 reviews  Read Recent Reviews

  • 2.1 miles Courtyard by Marriott Hotel North Lexington
    775 Newtown Court, Lexington, KY 40511
    2.1 miles from US 60 at US 421
    From $110
    Enter Dates
    Courtyard by Marriott Hotel North Lexington

    Check In1500
    Check Out1200

    Rated High
  • Upper-midscale, smoke-free, north Lexington hotel
  • Near KY 922
  • Heated indoor swimming pool - exercise room
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 262 reviews  Read Recent Reviews

  • 2.2 miles Hyatt Regency Hotel Lexington
    401 West High Street, Lexington, KY 40507
    2.2 miles from US 60 at US 421
    From $141
    Enter Dates
    Hyatt Regency Hotel Lexington

    Check In16 00
    Check Out11 00

    Rated High
  • Upscale, smoke-free, full-service, downtown hotel
  • Connected to Lexington Convention Center
  • Free 24-hour shuttle to Lexington Airport
  • Heated indoor swimming pool - 24-hour exercise room
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 1463 reviews  Read Recent Reviews

  • 2.3 miles Hilton Hotel Downtown Lexington
    369 West Vine Street, Lexington, KY 40507
    2.3 miles from US 60 at US 421
    From $147
    Enter Dates
    Hilton Hotel Downtown Lexington

    Check In15 00
    Check Out12 00

    Rated High
  • Upscale, smoke-free, full-service, downtown hotel
  • 2 blocks from Lexington Convention Center
  • Free shuttle to Lexington Airport
  • Heated indoor swimming pool - exercise room
  • Free WiFi
  • Parking costs $10 per night
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 1642 reviews  Read Recent Reviews

  • 2.3 miles SpringHill Suites by Marriott Downtown Lexington
    863 South Broadway, Lexington, KY 40508
    2.3 miles from US 60 at US 421
    From $144
    Enter Dates
    SpringHill Suites by Marriott Downtown Lexington

    Check In1500
    Check Out1200

    Rated High
  • Midscale, smoke-free, all-suite, downtown hotel
  • Near University of Kentucky
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking - truck parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 331 reviews  Read Recent Reviews

  • 2.4 miles 21c Museum Hotel Lexington
    167 West Main Street, Lexington, KY 40507
    2.4 miles from US 60 at US 421
    From $159
    Enter Dates
    21c Museum Hotel Lexington

    Check In1600
    Check Out1100

    Rated Very High
  • Luxury, smoke-free, full-service, boutique hotel
  • Near University of Kentucky
  • No swimming pool
  • 24-hour exercise room
  • Free WiFi
  • Valet parking only - $23 per night
  • Pet friendly hotel More >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 984 reviews  Read Recent Reviews

  • 2.5 miles Campbell House Hotel Lexington
    1375 South Broadway, Lexington, KY 40504
    2.5 miles from US 60 at US 421
    From $106
    Enter Dates
    Campbell House Hotel Lexington

    Check In15 00
    Check Out11 00

    Rated Average
  • Upscale, smoke-free, full-service, downtown hotel
  • A Curio Collection by Hilton hotel
  • Free shuttle to Lexington Airport
  • Heated indoor swimming pool - exercise room
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 1074 reviews  Read Recent Reviews

  • 2.5 miles Holiday Inn Express Hotel & Suites Downtown Lexington
    1000 Export Street, Lexington, KY 40504
    2.5 miles from US 60 at US 421
    From $111
    Enter Dates
    Holiday Inn Express Hotel & Suites Downtown Lexington

    Check In15 00
    Check Out11 00

    Rated High
  • Midscale, smoke-free, downtown hotel
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 251 reviews  Read Recent Reviews

  • 2.5 miles Sire Hotel Lexington
    120 West 2nd Street, Lexington, KY 40507
    2.5 miles from US 60 at US 421
    From $179
    Enter Dates
    Sire Hotel Lexington

    Check In16 00
    Check Out11 00

    Rated Very High
  • Upscale, smoke-free, full-service, downtown hotel
  • In Martin Luther King District
  • A Tapestry Collection by Hilton hotel
  • No swimming pool
  • Exercise room
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 77 reviews  Read Recent Reviews

  • 2.8 miles Embassy Suites Lexington
    1801 Newtown Pike, I-64, Exit 115, Lexington, KY 40511
    2.8 miles from US 60 at US 421
    From $144
    Enter Dates
    Embassy Suites Lexington

    Check In15 00
    Check Out11 00

    Rated High
  • Upscale, smoke-free, all-suite hotel
  • In north Lexington near I-64 at KY 922
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 1471 reviews  Read Recent Reviews

  • 3.0 miles Marriott Griffin Gate Resort Lexington
    1800 Newtown Pike, I-64, Exit 115, Lexington, KY 40511
    3.0 miles from US 60 at US 421
    From $139
    Enter Dates
    Marriott Griffin Gate Resort Lexington

    Check In1600
    Check Out1200

    Rated High
  • Upscale, smoke-free, full-service, golf resort
  • In north Lexington near KY 922 and I-64
  • Drop-off shuttle to local attractions costs $100 per person
  • Heated indoor swimming pool - outdoor pool
  • Exercise room
  • Golf course - full-service spa
  • Internet access costs $7 per night
  • Free parking
  • Pet friendly hotel More >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 905 reviews  Read Recent Reviews

  • 3.1 miles Clarion Hotel Lexington
    1950 Newtown Pike, I-64, Exit 115, Lexington, KY 40511
    3.1 miles from US 60 at US 421
    From $90
    Enter Dates
    Clarion Hotel Lexington

    Check In16 00
    Check Out11 00

    Rated Average
  • Upper-midscale, full-service hotel
  • In north Lexington near I-64
  • Free 24-hour shuttle to Lexington Airport
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 847 reviews  Read Recent Reviews

  • 3.4 miles Four Points by Sheraton Hotel Lexington
    1938 Stanton Way, I-64, Exit 115, Lexington, KY 40511
    3.4 miles from US 60 at US 421
    From $87
    Enter Dates
    Four Points by Sheraton Hotel Lexington

    Check In1500
    Check Out1200

    Rated Average
  • Upper-midscale, smoke-free, full-service hotel
  • In north Lexington near I-64 at KY 922
  • Free shuttle to Lexington Airport
  • Heated indoor-outdoor swimming pool - exercise room
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 197 reviews  Read Recent Reviews

  • 3.4 miles Fairfield Inn & Suites by Marriott North Lexington
    2100 Hackney Place, I-64, Exit 115, Lexington, KY 40511
    3.4 miles from US 60 at US 421
    From $79
    Enter Dates
    Fairfield Inn & Suites by Marriott North Lexington

    Check In1500
    Check Out1200

    Rated High
  • Midscale, smoke-free, north Lexington hotel
  • Located near I-64 at KY 922
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 408 reviews  Read Recent Reviews

  • 3.4 miles GLo Best Western Lexington Hotel
    1935 Stanton Way, I-64, Exit 115, Lexington, KY 40511
    3.4 miles from US 60 at US 421
    From $109
    Enter Dates
    GLo Best Western Lexington Hotel

    Check In1500
    Check Out1100

    Rated Very High
  • Upper-midscale, smoke-free hotel near I-64
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 116 reviews  Read Recent Reviews

  • 3.5 miles La Quinta Inn Lexington
    1920 Stanton Way, Lexington, KY 40511
    3.5 miles from US 60 at US 421
    From $59
    Enter Dates
    La Quinta Inn Lexington

    Check In15 00
    Check Out12 00

    Rated Low – Not Recommended
  • Midscale, north Lexington hotel near KY 922
  • Outdoor swimming pool open in summer
  • Free continental breakfast
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 546 reviews  Read Recent Reviews

  • 3.8 miles Red Roof Inn Lexington
    1980 Haggard Court, I-64, Exit 113, Lexington, KY 40505
    3.8 miles from US 60 at US 421
    From $50
    Enter Dates
    Red Roof Inn Lexington

    Check In13 00
    Check Out12 00

    Rated Average
  • Cheap, smoke-free motel near Thoroughbred Center
  • Also near I-64
  • No swimming pool
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 282 reviews  Read Recent Reviews

  • 3.8 miles Days Inn Lexington
    1987 North Broadway, I-64, Exit 113, Lexington, KY 40505
    3.8 miles from US 60 at US 421
    From $51
    Enter Dates
    Days Inn Lexington

    Check In1500
    Check Out1100

    Rated Low – Not Recommended
  • Cheap, full-service, interstate motel
  • Near Thoroughbred Center
  • Also near I-64
  • Some smoking rooms
  • Outdoor swimming pool open in summer - exercise room
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  2.5 of 5 stars
    Based on 904 reviews  Read Recent Reviews

  • 3.9 miles Residence Inn by Marriott Lexington
    3110 Wall Street, Lexington, KY 40513
    3.9 miles from US 60 at US 421
    From $89
    Enter Dates
    Residence Inn by Marriott Lexington

    Check In1600
    Check Out1200

    Rated Very High
  • Upscale, smoke-free, all-suite, extended-stay hotel
  • Near Beaumont Centre
  • Free shuttle to Lexington Airport
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 345 reviews  Read Recent Reviews

  • 3.9 miles TownePlace Suites by Marriott Airport Lexington
    980 Midnight Pass, Lexington, KY 40513
    3.9 miles from US 60 at US 421
    From $93
    Enter Dates
    TownePlace Suites by Marriott Airport Lexington

    Check In1500
    Check Out1200

    Rated Very High
  • Midscale, smoke-free, all-suite, extended-stay hotel
  • Near Beaumont Centre
  • Indoor swimming pool - 24-hour exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly hotel More >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 46 reviews  Read Recent Reviews

  • 3.9 miles Courtyard by Marriott Hotel Keenland Lexington
    3100 Wall Street, Lexington, KY 40513
    3.9 miles from US 60 at US 421
    From $93
    Enter Dates
    Courtyard by Marriott Hotel Keenland Lexington

    Check In1500
    Check Out1200

    Rated High
  • Upper-midscale, smoke-free, highway hotel
  • Near Beaumont Centre
  • Free shuttle to Lexington Airport
  • Heated indoor swimming pool - exercise room
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 201 reviews  Read Recent Reviews

  • 4.0 miles Fairfield Inn by Marriott Lexington
    3050 Lakecrest Circle, Lexington, KY 40513
    4.0 miles from US 60 at US 421
    From $84
    Enter Dates
    Fairfield Inn by Marriott Lexington

    Check In1500
    Check Out1200

    Rated High
  • Midscale, smoke-free hotel near Beaumont Centre
  • Free shuttle to Lexington Airport
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 81 reviews  Read Recent Reviews

  • 4.1 miles Hampton Inn Medical Center Lexington
    1953 Nicholasville Road, Lexington, KY 40503
    4.1 miles from US 60 at US 421
    From $108
    Enter Dates
    Hampton Inn Medical Center Lexington

    Check In15 00
    Check Out12 00

    Rated Very High
  • Midscale, smoke-free hotel near Fayette Mall
  • Free shuttle to Lexington Airport
  • Outdoor swimming pool open in summer - 24-hour exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 446 reviews  Read Recent Reviews

  • 4.1 miles Hampton Inn South Lexington
    3060 Lake Crest Circle, Lexington, KY 40513
    4.1 miles from US 60 at US 421
    From $96
    Enter Dates
    Hampton Inn South Lexington

    Check In15 00
    Check Out11 00

    Rated High
  • Midscale, smoke-free hotel near Beaumont Centre
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking - truck parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 444 reviews  Read Recent Reviews

  • 4.2 miles Ramada Inn & Conference Center Lexington
    2143 North Broadway, I-64, Exit 113, Lexington, KY 40505
    4.2 miles from US 60 at US 421
    From $56
    Enter Dates
    Ramada Inn & Conference Center Lexington

    Check In1500
    Check Out1200

    Rated Low – Not Recommended
  • Midscale, smoke-free hotel near Thoroughbred Center
  • Also near I-64
  • Free shuttle to Lexington Airport
  • Heated indoor swimming pool - outdoor pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free park and fly up to 7 nights only
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 1320 reviews  Read Recent Reviews

  • 4.7 miles Home2 Suites by Hilton Medical Center Lexington
    126 East Lowry Lane, Lexington, KY 40515
    4.7 miles from US 60 at US 421
    From $101
    Enter Dates
    Home2 Suites by Hilton Medical Center Lexington

    Check In15 00
    Check Out12 00

    Rated Very High
  • Midscale, smoke-free, all-suite hotel near Fayette Mall
  • Indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 779 reviews  Read Recent Reviews

  • 5 miles Homewood Suites by Hilton Fayette Mall Lexington
    249 Ruccio Way, Lexington, KY 40503
    5 miles from US 60 at US 421
    From $110
    Enter Dates
    Homewood Suites by Hilton Fayette Mall Lexington

    Check In15 00
    Check Out12 00

    Rated High
  • Upscale, smoke-free, all-suite, extended-stay hotel
  • Near Fayette Mall
  • Free shuttle to Lexington Airport
  • Free shuttle to other attractions within 2-mile radius
  • Outdoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Free park and fly up to 7 nights only
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 247 reviews  Read Recent Reviews

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Map of Hotels near US 60 at US 421



Nearby Attractions


Hotels near Rupp Arena   2.2 miles SE
Hotels near Lexington Convention Center   2.2 miles SE
Hotels near Lexington Opera House   2.2 miles SE
Hotels near Masterson Station Park   2.3 miles NW
Hotels near Transylvania University   2.4 miles SE
Hotels near Downtown Lexington   2.5 miles SE
Hotels near Good Samaritan Hospital Lexington   2.6 miles SE
Hotels near University of Kentucky College of Law   2.7 miles SE
Hotels near Memorial Coliseum   2.7 miles SE
Hotels near Singletary Center   2.8 miles SE
Hotels near Federal Medical Center Lexington   2.9 miles NW
Hotels near Whitaker Bank Ballpark   2.9 miles east
Hotels near Shriners Hospital Lexington   3.0 miles SE
Hotels near UK Albert B. Chandler Hospital   3.0 miles SE
Hotels near Lexington VA Medical Center   3.3 miles SE

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How Do We Order Hotels?

We order the hotels on this page by how close they are to this attraction.

Most of our competitors order these same hotels in other ways that make them more money.
How Do We Define Motel?

To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.

At hotels, on the other hand, you can enter your room only through a hall inside the building.
Lexington Hotel Tips

Important Hotel Tips


Hotels, Motels, Lodging, and Accommodations near US 60 at US 421 – Lexington, Kentucky KY, USA

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