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Hotels and Motels in James Island, South CarolinaTraveling to James Island, South Carolina? Then use this accommodations guide to learn about hotels, motels, and other lodging in or near James Island. James Island is located along South Carolina's central coast about 6 miles southwest of downtown Charleston, between Charleston Harbor to the north and Johns Island to the south. James Island County Park and golf courses are located in this area. The closest places to stay are on Folly Beach and in Charleston, on the west side of the Ashley River. James Island Group Hotel Rates 10 or more rooms
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