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Seneca, SC Hotels & Motels | HotelGuides.com
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Hotels > US Hotels > Hotels in South Carolina > Seneca Hotels & Motels

Hotels & Motels in or near or near Seneca, SC



Seneca is located in the northwestern tip of South Carolina, 8 miles west of Clemson. All of Seneca's hotels are north of downtown along US 76 and US 123.

 
  • Days Inn Seneca
    11015 Radio Station Road, Seneca, SC 29678 Call Us

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    Dates
    Days Inn Seneca

    Check In15 00
    Check Out11 00

    Rated Average
    • Cheap motel near Oconee Medical Center
    • 6 miles northwest of Oconee County Regional Airport
    • 2 floors, 63 rooms - no elevator
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 356 reviews 
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  • Quality Inn Seneca
    226 Hi-Tech Road, Seneca, SC 29678 Call Us

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    Dates
    Quality Inn Seneca

    Check In15 00
    Check Out11 00

    Rated Average
    • Midscale, smoke-free motel 3 miles from downtown
    • 2 floors, 62 rooms - no elevator
    • Outdoor swimming pool open in summer
    • Free continental breakfast
    • Free WiFi
    • Free parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 62 reviews 
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  • Best Western Seneca Clemson Hotel
    511 US 123 Bypass, Seneca, SC 29678 Call Us

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    Dates
    Best Western Seneca Clemson Hotel

    Check In1400
    Check Out1100

    Rated High
    • Midscale, smoke-free hotel 9 miles northeast of Clemson
    • 3 floors, 58 rooms and suites - elevator
    • Outdoor swimming pool open in summer
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 229 reviews 
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  • Hampton Inn & Suites Seneca
    1011 East North 1st Street, Seneca, SC 29679 Call Us

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    Dates
    Hampton Inn & Suites Seneca

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free, highway hotel
    • Near US 123
    • 1.5 miles northeast of downtown Seneca
    • 4 floors, 100 rooms and suites
    • Outdoor swimming pool open in summer
    • Exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 562 reviews 
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  • Tru by Hilton Hotel Seneca
    13050 Clemson Blvd, Seneca, SC 29678 Call Us

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    Dates
    Tru by Hilton Hotel Seneca

    Check In15 00
    Check Out12 00

    Rated High
    • Midscale, smoke-free hotel near Lake Hartwell 4 floors, 98 rooms
    • Exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 114 reviews 
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  • Fairfield Inn & Suites by Marriott Seneca
    800 Bypass 123, Seneca, SC 29678 Call Us

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    Dates
    Fairfield Inn & Suites by Marriott Seneca

    Check In1500
    Check Out1100

    Rated High
    • Upper-midscale, smoke-free hotel
    • 2 miles from Oconee Medical Center
    • 4 floors, 102 rooms and suites
    • Outdoor swimming pool open in summer
    • 24-hour exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 4 reviews 
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  • Hampton Inn Clemson
    851 Tiger Blvd, Clemson, SC 29631 Call Us 6 miles
    6 miles from Seneca

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    Dates
    Hampton Inn Clemson

    Check In15 00
    Check Out11 00

    Rated High
    • Upper-midscale, smoke-free hotel near US 123
    • 1.5 miles northwest of Clemson University
    • 4 floors, 90 rooms
    • Outdoor swimming pool open in summer Exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 509 reviews 
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  • Abernathy Hotel Clemson
    157 Old Greenville Highway, Clemson, SC 29631 Call Us 6 miles
    6 miles from Seneca

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    Dates
    Abernathy Hotel Clemson

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upscale, smoke-free hotel near Clemson University
    • 4 floors, 41 rooms
    • No swimming pool
    • Restaurant - lounge
    • Restaurant open for breakfast and dinner only
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 266 reviews 
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  • James F. Martin Inn Clemson
    240 Madren Center Drive, Clemson, SC 29634 Call Us 6 miles
    6 miles from Seneca

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    Dates
    James F. Martin Inn Clemson

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free hotel
    • Connected to Madren Conference Center
    • 4 floors, 89 rooms and suites
    • Outdoor swimming pool open in summer Exercise room
    • Restaurant - lounge - cafe
    • Restaurant open for lunch and dinner only
    • Cafe open for breakfast only
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 273 reviews 
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  • Comfort Inn Clemson
    1305 Tiger Blvd, Clemson, SC 29631 Call Us 7 miles
    7 miles from Seneca

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    Dates
    Comfort Inn Clemson

    Check In16 00
    Check Out12 00

    Rated High
    • Midscale, smoke-free hotel near US 123
    • Near Clemson University and SC Botanical Garden
    • Outdoor swimming pool open in summer Exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 172 reviews 
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  • Holiday Inn Express & Suites Clemson
    1381 Tiger Blvd, Clemson, SC 29631 Call Us 8 miles
    8 miles from Seneca

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    Dates
    Holiday Inn Express & Suites Clemson

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free hotel near US 123
    • 1 mile northeast of Clemson University
    • 4 floors, 93 rooms and suites
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 233 reviews 
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  • Days Inn Clemson
    1387 Tiger Blvd, Clemson, SC 29631 Call Us 8 miles
    8 miles from Seneca

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    Dates
    Days Inn Clemson

    Check In15 00
    Check Out11 00

    Rated Average
    • Cheap motel near US 123
    • Also near Clemson University and SC Botanical Garden
    • 2 floors, 44 rooms - no elevator
    • Some smoking rooms
    • No swimming pool
    • Free continental breakfast
    • Free WiFi
    • Free parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 284 reviews 
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  • Rodeway Inn & Suites Walhalla
    901 East Main Street, Walhalla, SC 29691 Call Us 8 miles
    8 miles from Seneca

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    Dates
    Rodeway Inn & Suites Walhalla

    Check In15 00
    Check Out11 00

    Rated Average
    • Cheap motel on eastern edge of downtown
    • Single-story, 20 rooms and suites
    • Some smoking rooms
    • No swimming pool
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 35 reviews 
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  • Courtyard by Marriott Hotel Clemson
    201 Canoy Lane, Clemson, SC 29631 Call Us 8 miles
    8 miles from Seneca

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    Dates
    Courtyard by Marriott Hotel Clemson

    Check In1500
    Check Out1200

    Rated Very High
    • Upscale, smoke-free hotel near US 123
    • 2 miles northeast of Clemson University
    • 6 floors, 110 rooms and suites
    • Heated outdoor swimming pool open in summer
    • Exercise room
    • Restaurant - lounge
    • Restaurant open for breakfast and dinner only
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 234 reviews 
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  • Inn at Patrick Square Clemson
    115 Market Street, Clemson, SC 29631 Call Us 9 miles
    9 miles from Seneca

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    Dates
    Inn at Patrick Square Clemson

    Check In16 00
    Check Out11 00

    • Midscale, smoke-free hotel
    • 4 miles from Clemson University
    • 4 floors, 45 rooms and suites
    • No swimming pool
    • Free WiFi
    • Free parking
    • Not pet friendly

  • Microtel Inn & Suites by Wyndham Anderson - I-85, Exit 19B
    102 Electric City Blvd, I-85, Exit 19B, Anderson, SC 29621 Call Us 15 miles
    15 miles from Seneca

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    Dates
    Microtel Inn & Suites by Wyndham Anderson - I-85, Exit 19B

    Check In15 00
    Check Out11 00

    Rated High
    • Cheap, smoke-free hotel near I-85
    • 4.5 miles from Anderson Mall
    • 4 floors, 69 rooms and suites
    • Outdoor swimming pool open in summer
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 591 reviews 
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  • Holiday Inn Express & Suites Anderson - I-85, Exit 19B
    107 Interstate Blvd, I-85, Exit 19B, Anderson, SC 29621 Call Us 16 miles
    16 miles from Seneca

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    Dates
    Holiday Inn Express & Suites Anderson - I-85, Exit 19B

    Check In15 00
    Check Out11 00

    Rated High
    • Upper-midscale, smoke-free hotel near I-85
    • 4 miles from Anderson Mall
    • 3 floors, 75 rooms and suites - elevator
    • Outdoor swimming pool open in summer
    • Exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 101 reviews 
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  • Residence Inn by Marriott Clemson Anderson - I-85, Exit 19B
    109 Interstate Blvd, I-85, Exit 19B, Anderson, SC 29621 Call Us 16 miles
    16 miles from Seneca

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    Dates
    Residence Inn by Marriott Clemson Anderson - I-85, Exit 19B

    Check In1500
    Check Out1200

    Rated Very High
    • Upscale, smoke-free, all-suite, extended-stay hotel
    • 4.5 miles from Anderson Mall
    • 4 floors, 94 studio and 1-bedroom suites
    • Outdoor swimming pool open in summer Exercise room
    • Kitchen in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 5 reviews 
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  • Fairfield Inn & Suites by Marriott Anderson - I-85, Exit 19B
    117 Interstate Blvd, I-85, Exit 19B, Anderson, SC 29621 Call Us 16 miles
    16 miles from Seneca

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    Dates
    Fairfield Inn & Suites by Marriott Anderson - I-85, Exit 19B

    Check In1600
    Check Out1100

    Rated High
    • Upper-midscale, smoke-free hotel near I-85
    • 7 miles from Anderson University
    • 3 floors, 79 rooms and suites - elevator
    • Outdoor swimming pool open in summer Exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 123 reviews 
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  • Country Inn & Suites by Radisson Anderson - I-85, Exit 19B
    116 Interstate Blvd, I-85, Exit 19B, Anderson, SC 29621 Call Us 16 miles
    16 miles from Seneca

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    Dates
    Country Inn & Suites by Radisson Anderson - I-85, Exit 19B

    Check In15 00
    Check Out11 00

    Rated High
    • Upper-midscale, smoke-free hotel near I-85
    • 4.5 miles from Anderson Mall
    • Heated indoor swimming pool - exercise room
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 549 reviews 
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Seneca Info

Pet Friendly Hotels in or near Seneca

Seneca Group Hotel Rates

Hotels near Me

Nearby Attractions


Hotels near Littlejohn Coliseum   6 miles east
Hotels near Memorial Stadium   6 miles east
Hotels near Clemson University   7 miles east
Hotels near Oconee Nuclear Station   8 miles NE
Hotels near T. Ed Garrison Arena   9 miles east
Hotels near Southern Wesleyan University   11 miles east
Hotels near Boxwood Manor   14 miles SE
Hotels near South Carolina Georgia Border at I-85   14 miles south
Hotels near Tugaloo State Park   15 miles SW
Hotels near Green Pond Landing   15 miles SE
Hotels near Oconee State Park   15 miles NW
Hotels near Clemson Blvd Anderson   18 miles SE
Hotels near Anderson Sports and Entertainment Center   19 miles SE
Hotels near Anderson Civic Center   19 miles SE
Hotels near Anderson Mall   19 miles SE

Nearby Cities


Clemson SC Hotels   7 miles east
Westminster SC Hotels   8 miles west
Walhalla SC Hotels   8 miles NW
Pendleton SC Hotels   10 miles east
Central SC Hotels   10 miles east
Six Mile SC Hotels   11 miles NE
Liberty SC Hotels   16 miles NE
Lavonia GA Hotels   19 miles SW
Pickens SC Hotels   20 miles NE
Anderson SC Hotels   21 miles SE
Toccoa GA Hotels   22 miles west
Easley SC Hotels   22 miles NE
Hartwell GA Hotels   23 miles south
Pumpkintown SC Hotels   28 miles NE
Piedmont SC Hotels   28 miles east
How Do We Order Hotels?

On place pages like this, we order hotels from lowest cost to highest – except we list low-rated hotels at the bottom of the page.

Most of our competitors order these same hotels in other ways that make them more money.
How Do We Define Motel?

To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.

At hotels, on the other hand, you can enter your room only through a hall inside the building.
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Hotel Booking Tips
  1. Beware of non-refundable reservations that could cost you a lot of money if you change or cancel them. +Non-refundable reservations are a gamble that will usually save you less than $10. If you make a $90 non-refundable reservation instead of a $100 refundable booking, you are betting $90 to win $10. Would you do that in Las Vegas?
  2. Don't assume you can cancel a non-refundable reservation without penalty if you notify the hotel weeks or even months in advance. +Often you cannot – because some hotels' profit strategy is to get paid more than once for the same room for the same night.
  3. Always read cancellation policies carefully before you make a reservation. + When is the latest date and time you can cancel without penalty?
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  4. When you make a reservation, you will receive a confirmation email. Take a copy with you to the hotel.
  5. The earlier in the afternoon you check into a hotel, the more likely you will get a room or suite that matches your preferences.



Seneca Hotels, Motels, Lodging, and Accommodations – Seneca, South Carolina SC, USA

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