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Hotels and Motels in Santee, South Carolina

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Best Value hotels below are sorted by price – except hotels rated below average are listed at bottom, regardless of price.

Santee, the freshwater fishing capital of South Carolina, lies on the southwestern shore of Lake Marion, midway between Charleston and Columbia. All of Santee's hotels are near I-95, Exit 98.

If you need help finding a hotel that is open, call us at 1-800-916-4526.
Map of Santee, SC Hotels and Motels
 

    Hotels in or near Santee

    Rates shown below are averages. Click See Rates to see rates for your dates.
  • Red Roof Inn Santee
    9091 Old SC 6, I-95, Exit 98, Santee, SC 29142

    From $53
    Enter Dates
    Red Roof Inn Santee

    Check In15 00
    Check Out11 00

    Rated Average
  • Cheap motel near I-95
  • 2 miles from Santee State Park
  • Single-story, 40 rooms
  • No swimming pool
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 178 reviews  Read Recent Reviews

  • Travelodge Santee
    9117 Old SC 6, I-95, Exit 98, Santee, SC 29142

    From $54
    Enter Dates
    Travelodge Santee

    Check In1400
    Check Out1100

    Rated Average
  • Cheap motel near I-95 and Santee Outlet Mall
  • Single-story, 34 rooms
  • Some smoking rooms
  • Outdoor swimming pool open in summer
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 67 reviews  Read Recent Reviews

  • Super 8 Hotel Santee
    9125 Old SC 6, I-95, Exit 98, Santee, SC 29142

    From $59
    Enter Dates
    Super 8 Hotel Santee

    Check In1500
    Check Out1100

    Rated Average
  • Cheap motel near I-95
  • 2 miles from Santee State Park
  • Single-story, 42 rooms
  • Outdoor swimming pool open in summer
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 355 reviews  Read Recent Reviews

  • Best Western Plus Santee Inn
    9059 Old SC 6, I-95, Exit 98, Santee, SC 29142

    From $85
    Enter Dates
    Best Western Plus Santee Inn

    Check In1400
    Check Out1100

    Rated High
  • Upper-midscale hotel near I-95 and Santee Outlet Mall
  • Outdoor swimming pool open in summer - exercise room
  • Free continental breakfast
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 1298 reviews  Read Recent Reviews

  • Fairfield Inn & Suites by Marriott Santee
    9074 Old Number Six Highway, Santee, SC 29142

    From $118
    Enter Dates
    Fairfield Inn & Suites by Marriott Santee

    Check In1500
    Check Out1200

    Rated Very High
  • Midscale, smoke-free, interstate hotel
  • Outdoor swimming pool open in summer - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 46 reviews  Read Recent Reviews

  • Holiday Inn Santee
    139 Bradford Blvd, I-95, Exit 98, Santee, SC 29142

    From $126
    Enter Dates
    Holiday Inn Santee

    Check In15 00
    Check Out11 00

    Rated Average
  • Upper-midscale hotel near I-95
  • 2 miles from Santee State Park
  • Heated indoor swimming pool - exercise room
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 287 reviews  Read Recent Reviews

  • Hampton Inn Santee
    9060 Old SC 6, I-95, Exit 98, Santee, SC 29142

    From $136
    Enter Dates
    Hampton Inn Santee

    Check In15 00
    Check Out11 00

    Rated Very High
  • Midscale, smoke-free hotel near I-95 at US 301
  • Outdoor swimming pool open in summer - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >


  • Clarion Inn Santee
    123 Mall Street, I-95, Exit 98, Santee, SC 29142

    From $47
    Enter Dates
    Clarion Inn Santee

    Check In15 00
    Check Out11 00

    Rated Very Low – Not Recommended
  • Upper-midscale, smoke-free motel near I-95
  • Outdoor swimming pool open in summer - exercise room
  • Free WiFi
  • Free parking - truck parking
  • Not pet friendly - no pets allowed.
    TripAdvisor Traveler Rating:  2.5 of 5 stars
    Based on 160 reviews  Read Recent Reviews

  • Econo Lodge Santee
    9112 Old SC 6, I-95, Exit 98, Santee, SC 29142

    From $59
    Enter Dates
    Econo Lodge Santee

    Check In14 00
    Check Out11 00

    Rated Very Low – Not Recommended
  • Cheap motel near I-95 and Santee Outlet Mall
  • Single-story, 77 rooms
  • Outdoor swimming pool open in summer
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >


  • Quality Inn & Suites Santee
    8929 Old SC 6, I-95, Exit 98, Santee, SC 29142

    From $81
    Enter Dates
    Quality Inn & Suites Santee

    Check In15 00
    Check Out11 00

    Rated Low – Not Recommended
  • Midscale motel near I-95 at US 301
  • Outdoor swimming pool open in summer - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  2.5 of 5 stars
    Based on 83 reviews  Read Recent Reviews

  • 10 miles Days Inn Summerton
    400 Buff Blvd, I-95, Exit 108, Summerton, SC 29148
    10 miles from Santee
    From $58
    Enter Dates
    Days Inn Summerton

    Check In1400
    Check Out1100

    Rated Average
  • Cheap motel 1 mile south of downtown
  • Outdoor swimming pool open in summer
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 219 reviews  Read Recent Reviews

  • 15 miles Days Inn South Orangeburg
    3402 Five Chop Road, I-26, Exit 154B, Orangeburg, SC 29115
    15 miles from Santee
    From $60
    Enter Dates
    Days Inn South Orangeburg

    Check In1500
    Check Out1100

    Rated Average
  • Cheap motel near I-26 at US 301
  • Outdoor swimming pool open in summer
  • Free continental breakfast
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 220 reviews  Read Recent Reviews

  • 20 miles Quality Inn Manning
    3031 Paxville Highway, I-95, Exit 119, Manning, SC 29102
    20 miles from Santee
    From $76
    Enter Dates
    Quality Inn Manning

    Check In14 00
    Check Out11 00

    Rated Average
  • Midscale motel near I-95
  • Outdoor swimming pool open in summer
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 153 reviews  Read Recent Reviews

  • 20 miles Baymont Inn & Suites Manning
    2284 Racoon Road, I-95, Exit 119, Manning, SC 29102
    20 miles from Santee
    From $68
    Enter Dates
    Baymont Inn & Suites Manning

    Check In1500
    Check Out1100

    Rated Average
  • Midscale, smoke-free motel near I-95
  • Outdoor swimming pool open in summer - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 1438 reviews  Read Recent Reviews

  • 20 miles Days Inn Manning
    2825 Paxville Highway, I-95, Exit 119, Manning, SC 29102
    20 miles from Santee
    From $59
    Enter Dates
    Days Inn Manning

    Check In1400
    Check Out1100

    Rated Very Low – Not Recommended
  • Cheap motel near I-95
  • Outdoor swimming pool open in summer
  • Free continental breakfast
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    TripAdvisor Traveler Rating:  2.0 of 5 stars
    Based on 197 reviews  Read Recent Reviews

  • 20 miles SureStay Hotel by Best Western Manning
    2816 Paxville Highway, I-95, Exit 119, Manning, SC 29102
    20 miles from Santee
    From $65
    Enter Dates
    SureStay Hotel by Best Western Manning

    Check In1400
    Check Out1100

    Rated High
  • Cheap, smoke-free, interstate motel near I-95
  • No swimming pool
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 397 reviews  Read Recent Reviews

  • 20 miles Fairfield Inn by Marriott Orangeburg
    663 Citadel Road, I-26, Exit 145, Orangeburg, SC 29115
    20 miles from Santee
    From $114
    Enter Dates
    Fairfield Inn by Marriott Orangeburg

    Check In1500
    Check Out1200

    Rated Average
  • Midscale, smoke-free hotel near I-26 at US 601
  • 1 mile east of Orangeburg-Calhoun Hospital
  • Outdoor swimming pool open in summer - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 163 reviews  Read Recent Reviews

  • 20 miles Hampton Inn Manning
    2822 Paxville Highway, I-95, Exit 119, Manning, SC 29102
    20 miles from Santee
    From $123
    Enter Dates
    Hampton Inn Manning

    Check In15 00
    Check Out11 00

    Rated Average
  • Midscale, smoke-free hotel near I-95
  • 1 mile from downtown Manning
  • Outdoor swimming pool open in summer - exercise room
  • Free continental breakfast
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 672 reviews  Read Recent Reviews

  • 20 miles Country Inn & Suites by Radisson Orangeburg
    731 Citadel Road, I-26, Exit 145, Orangeburg, SC 29117
    20 miles from Santee
    From $125
    Enter Dates
    Country Inn & Suites by Radisson Orangeburg

    Check In15 00
    Check Out12 00

    Rated Average
  • Midscale, smoke-free hotel near I-26 at US 601
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 745 reviews  Read Recent Reviews

  • 21 miles Tru by Hilton Hotel Orangeburg
    739 Citadel Road, I-26, Exit 145, Orangeburg, SC 29118
    21 miles from Santee
    From $105
    Enter Dates
    Tru by Hilton Hotel Orangeburg

    Check In15 00
    Check Out12 00

    Rated Very High
  • Midscale, smoke-free hotel near I-26 at US 601
  • No swimming pool
  • Exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 124 reviews  Read Recent Reviews

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Santee Info

Pet Friendly Hotels in or near Santee

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Hotels near Me

Nearby Attractions


Hotels near Santee National Wildlife Refuge   4.3 miles NE
Hotels near Yonder Field   14 miles SW
Hotels near Oliver Dawson Stadium   21 miles west
Hotels near Claflin University   22 miles west
Hotels near South Carolina State University   22 miles west
Hotels near World Grits Festival – St George SC   24 miles south
Hotels near Congaree National Park   27 miles NW
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Nearby Cities


Summerton SC Hotels   11 miles NE
Holly Hill SC Hotels   12 miles south
Harleyville SC Hotels   19 miles south
Manning SC Hotels   21 miles NE
St George SC Hotels   22 miles south
Orangeburg SC Hotels   23 miles west
Eastover SC Hotels   30 miles NW
How Do We Order Hotels?

On place pages like this, we order hotels from lowest cost to highest – except we list low-rated hotels at the bottom of the page.

Most of our competitors order these same hotels in other ways that make them more money.
How Do We Define Motel?

To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.

At hotels, on the other hand, you can enter your room only through a hall inside the building.
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Important Hotel Tips


Santee Hotels near Me

Santee Hotels, Motels, Lodging, and Accommodations – Santee, South Carolina SC, USA

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