Hotels near I-95 at US 52 in Florence, SC | HotelGuides.com
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Hotel Guides > Interstate Hotels > I-95 > Hotels near I-95 at US 52, Exit 164

Hotels near I-95 at US 52, Exit 164 – Florence, South Carolina


The hotels below are listed in order of their exit number.

Map of Hotels and Motels near I-95 at US 52, Exit 164
 

    Hotels closest to I-95 at US 52, Exit 164

    Rates shown below are averages. Click See Rates to see rates for your dates.
  • 0.1 mile Comfort Suites Florence
    2120 West Lucas Street, Florence, SC 29501
    0.1 mile from I-95 at US 52, Exit 164
    From $100
    Enter Dates
    Comfort Suites Florence

    Check In15 00
    Check Out11 00

    Rated High
  • Midscale, smoke-free, all-suite hotel
  • Near I-95 at US 52
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 529 reviews  Read Recent Reviews

  • 0.2 mile Country Inn & Suites by Radisson Florence
    1739 Mandeville Road, Florence, SC 29501
    0.2 mile from I-95 at US 52, Exit 164
    From $94
    Enter Dates
    Country Inn & Suites by Radisson Florence

    Check In15 00
    Check Out12 00

    Rated High
  • Midscale, smoke-free hotel near I-95 at US 52
  • Outdoor swimming pool open in summer - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 877 reviews  Read Recent Reviews

  • 0.2 mile Knights Inn Florence
    1834 West Lucas Street, Florence, SC 29501
    0.2 mile from I-95 at US 52, Exit 164
    From $44
    Enter Dates
    Knights Inn Florence

    Check In1500
    Check Out1100

    Rated Very Low – Not Recommended
  • Cheap, smoke-free motel near I-95 at US 52
  • Single-story, 109 rooms
  • Outdoor swimming pool open in summer
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    TripAdvisor Traveler Rating:  2.0 of 5 stars
    Based on 92 reviews  Read Recent Reviews

  • 0.2 mile Best Western Inn Florence
    1808 West Lucas Street, Florence, SC 29501
    0.2 mile from I-95 at US 52, Exit 164
    From $76
    Enter Dates
    Best Western Inn Florence

    Check In1500
    Check Out1100

    Rated Average
  • Midscale motel near I-95 at US 52
  • Outdoor swimming pool open in summer
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 493 reviews  Read Recent Reviews

  • 0.2 mile Howard Johnson Express Inn Northwest Florence
    2038 West Lucas Street, Florence, SC 29501
    0.2 mile from I-95 at US 52, Exit 164
    From $58
    Enter Dates
    Howard Johnson Express Inn Northwest Florence

    Check In1500
    Check Out1100

    Rated High
  • Cheap motel near I-95 at US 52
  • Outdoor swimming pool - exercise room
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 468 reviews  Read Recent Reviews

  • 0.3 mile Super 8 Hotel Florence
    1832 1/2 West Lucas Street, Florence, SC 29501
    0.3 mile from I-95 at US 52, Exit 164
    From $148
    Enter Dates
    Super 8 Hotel Florence

    Check In1400
    Check Out1100

    Rated Average
  • Cheap motel near I-95 at US 52
  • Outdoor swimming pool open in summer
  • Free continental breakfast
  • Free WiFi
  • Free parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 407 reviews  Read Recent Reviews

  • 0.3 mile Hampton Inn & Suites North I-95 Florence
    1735 Stokes Road, Florence, SC 29501
    0.3 mile from I-95 at US 52, Exit 164
    From $126
    Enter Dates
    Hampton Inn & Suites North I-95 Florence

    Check In15 00
    Check Out12 00

    Rated Very High
  • Midscale, smoke-free hotel near I-95 at US 52
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking - truck parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 1191 reviews  Read Recent Reviews

  • 0.4 mile Baymont Inn & Suites Florence
    1826 West Lucas Street, Florence, SC 29501
    0.4 mile from I-95 at US 52, Exit 164
    From $62
    Enter Dates
    Baymont Inn & Suites Florence

    Check In15 00
    Check Out11 00

    Rated Average
  • Midscale motel near I-95 at US 52
  • Outdoor swimming pool open in summer - exercise room
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 1843 reviews  Read Recent Reviews

  • 0.4 mile Days Inn I-95 North Florence
    2111 West Lucas Street, Florence, SC 29501
    0.4 mile from I-95 at US 52, Exit 164
    From $60
    Enter Dates
    Days Inn I-95 North Florence

    Check In1500
    Check Out1100

    Rated Average
  • Cheap motel near I-95 at US 52
  • Outdoor swimming pool open in summer
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 925 reviews  Read Recent Reviews

  • 0.4 mile Econo Lodge Florence
    1920 West Lucas Street, Florence, SC 29501
    0.4 mile from I-95 at US 52, Exit 164
    From $81
    Enter Dates
    Econo Lodge Florence

    Check In14 00
    Check Out11 00

    Rated Low – Not Recommended
  • Cheap motel near I-95 at US 52
  • Outdoor swimming pool - exercise room
  • Free continental breakfast
  • Free WiFi
  • Free parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 244 reviews  Read Recent Reviews

  • 0.5 mile La Quinta Inn & Suites Florence
    2123 West Lucas Street, Florence, SC 29501
    0.5 mile from I-95 at US 52, Exit 164
    From $89
    Enter Dates
    La Quinta Inn & Suites Florence

    Check In15 00
    Check Out12 00

    Rated Average
  • Midscale, smoke-free hotel near I-95 at US 52
  • Outdoor swimming pool open in summer - exercise room
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 1055 reviews  Read Recent Reviews

  • 0.5 mile Tru by Hilton Hotel I-95 Florence
    2140 West Lucas Street, Florence, SC 29501
    0.5 mile from I-95 at US 52, Exit 164
    From $115
    Enter Dates
    Tru by Hilton Hotel I-95 Florence

    Check In15 00
    Check Out12 00

    Rated High
  • Midscale, smoke-free hotel near I-95 at US 52
  • Indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 104 reviews  Read Recent Reviews

  • 0.7 mile Microtel Inn & Suites by Wyndham Florence
    1912 Enterprise Drive, Florence, SC 29502
    0.7 mile from I-95 at US 52, Exit 164
    From $51
    Enter Dates
    Microtel Inn & Suites by Wyndham Florence

    Check In1500
    Check Out1100

    Rated Average
  • Cheap, smoke-free hotel near I-95 at US 52
  • No swimming pool
  • Free continental breakfast
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 297 reviews  Read Recent Reviews

  • 2.9 miles Hotel Florence
    126 West Evans Street, Florence, SC 29501
    2.9 miles from I-95 at US 52, Exit 164
    From $126
    Enter Dates
    Hotel Florence

    Check In16 00
    Check Out11 00

    Rated Very High
  • Midscale, smoke-free, full-service, downtown hotel
  • An Ascend Hotel Collection Member
  • Near I-95 - 3 miles from Florence Airport
  • No shuttle to Florence Airport
  • No swimming pool
  • Exercise room
  • Free WiFi
  • Free parking
  • Free park and fly up to 7 nights only
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 547 reviews  Read Recent Reviews

  • 3.0 miles Hyatt Place Hotel Downtown Florence
    100 East Evans Street, Florence, SC 29506
    3.0 miles from I-95 at US 52, Exit 164
    From $114
    Enter Dates
    Hyatt Place Hotel Downtown Florence

    Check In15 00
    Check Out11 00

    Rated High
    Upper-midscale, smoke-free, full-service, downtown hotel Near I-95
  • Outdoor swimming pool - exercise room
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 32 reviews  Read Recent Reviews

  • 3.4 miles Red Roof Inn Florence
    2690 David McLeod Blvd, I-20, Exit 141A, Florence, SC 29501
    3.4 miles from I-95 at US 52, Exit 164
    From $59
    Enter Dates
    Red Roof Inn Florence

    Check In15 00
    Check Out11 00

    Rated Average
  • Cheap, smoke-free motel near I-95
  • Also near Florence Civic Center
  • No swimming pool
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 430 reviews  Read Recent Reviews

  • 3.5 miles Quality Inn & Suites Civic Center Florence
    150 Dunbarton Drive, I-20, Exit 141, Florence, SC 29501
    3.5 miles from I-95 at US 52, Exit 164
    From $90
    Enter Dates
    Quality Inn & Suites Civic Center Florence

    Check In14 00
    Check Out12 00

    Rated High
  • Midscale motel near Florence Center
  • Also near I-95, I-20, and Florence Mall
  • Some smoking rooms
  • Outdoor swimming pool open in summer - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 311 reviews  Read Recent Reviews

  • 3.5 miles Days Inn Civic Center Florence
    140 Dunbarton Drive, I-20, Exit 141, Florence, SC 29501
    3.5 miles from I-95 at US 52, Exit 164
    From $62
    Enter Dates
    Days Inn Civic Center Florence

    Check In1500
    Check Out1100

    Rated Average
  • Cheap, smoke-free motel near Florence Center
  • Also near Magnolia Mall and I-95 at I-20
  • Outdoor swimming pool - exercise room
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 700 reviews  Read Recent Reviews

  • 3.5 miles Fairfield Inn & Suites by Marriott Florence
    501 Woody Jones Blvd, Florence, SC 29501
    3.5 miles from I-95 at US 52, Exit 164
    From $122
    Enter Dates
    Fairfield Inn & Suites by Marriott Florence

    Check In1600
    Check Out1100

    Rated Very High
  • Midscale, smoke-free hotel near Florence Center
  • Indoor swimming pool - 24-hour exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking - truck parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 158 reviews  Read Recent Reviews

  • 3.6 miles Hilton Garden Inn Florence
    2671 Hospitality Blvd, Florence, SC 29501
    3.6 miles from I-95 at US 52, Exit 164
    From $116
    Enter Dates
    Hilton Garden Inn Florence

    Check In15 00
    Check Out12 00

    Rated Very High
  • Upper-midscale, smoke-free hotel near I-95
  • Also near Florence Center
  • Heated indoor swimming pool - exercise room
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 1010 reviews  Read Recent Reviews

  • 3.6 miles Hampton Inn & Suites Civic Center Florence
    3000 Radio Drive, Florence, SC 29501
    3.6 miles from I-95 at US 52, Exit 164
    From $126
    Enter Dates
    Hampton Inn & Suites Civic Center Florence

    Check In15 00
    Check Out12 00

    Rated Very High
  • Midscale, smoke-free hotel near I-95 and civic center
  • Also near GE and Magnolia Mall
  • Outdoor swimming pool open in summer
  • Exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 602 reviews  Read Recent Reviews

  • 3.6 miles Residence Inn by Marriott Florence
    2660 Hospitality Blvd, Florence, SC 29501
    3.6 miles from I-95 at US 52, Exit 164
    From $131
    Enter Dates
    Residence Inn by Marriott Florence

    Check In1600
    Check Out1100

    Rated Very High
  • Upscale, smoke-free, all-suite, extended-stay hotel
  • Near Florence Center
  • Outdoor swimming pool open in summer
  • Exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 439 reviews  Read Recent Reviews

  • 3.6 miles SpringHill Suites by Marriott Florence
    2670 Hospitality Blvd, Florence, SC 29501
    3.6 miles from I-95 at US 52, Exit 164
    From $122
    Enter Dates
    SpringHill Suites by Marriott Florence

    Check In1600
    Check Out1100

    Rated Very High
  • Midscale, smoke-free, all-suite hotel near I-95
  • Also near Florence Civic Center
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking - truck parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 591 reviews  Read Recent Reviews

  • 3.6 miles TownePlace Suites by Marriott Florence
    2650 Hospitality Blvd, Florence, SC 29501
    3.6 miles from I-95 at US 52, Exit 164
    From $131
    Enter Dates
    TownePlace Suites by Marriott Florence

    Check In1600
    Check Out1100

    Rated Very High
  • Midscale, smoke-free, all-suite, extended-stay hotel
  • Near Florence Center and I-95 at I-20
  • Outdoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 229 reviews  Read Recent Reviews

  • 3.7 miles Courtyard by Marriott Hotel Florence
    2680 Hospitality Blvd, Florence, SC 29501
    3.7 miles from I-95 at US 52, Exit 164
    From $114
    Enter Dates
    Courtyard by Marriott Hotel Florence

    Check In1600
    Check Out1100

    Rated Very High
  • Upper-midscale, smoke-free hotel
  • Near Florence Center
  • Heated indoor swimming pool - exercise room
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 527 reviews  Read Recent Reviews

  • 3.7 miles Affordable Suites of America Florence
    530 Woody Jones Blvd, Florence, SC 29501
    3.7 miles from I-95 at US 52, Exit 164
    From $588
    Enter Dates
    Affordable Suites of America Florence

    Check In13 00
    Check Out11 00

    Rated Very High
  • Budget, all-suite, extended-stay motel
  • Near Florence Center
  • No swimming pool
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Note: This motel does not allow children.
    TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 40 reviews  Read Recent Reviews

  • 3.8 miles Comfort Inn & Suites Florence
    527 Woody Jones Blvd, Florence, SC 29501
    3.8 miles from I-95 at US 52, Exit 164
    From $144
    Enter Dates
    Comfort Inn & Suites Florence

    Check In16 00
    Check Out11 00

    Rated Very High
  • Midscale, smoke-free hotel near Florence Center
  • Outdoor swimming pool open in summer - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking - limited truck parking
  • Pet friendly hotel More >
    TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 9 reviews  Read Recent Reviews

  • 3.9 miles Home2 Suites by Hilton Florence
    900 Woody Jones Blvd, Florence, SC 29501
    3.9 miles from I-95 at US 52, Exit 164
    From $135
    Enter Dates
    Home2 Suites by Hilton Florence

    Check In15 00
    Check Out11 00

    Rated Very High
  • Midscale, smoke-free, all-suite, extended-stay hotel
  • Near Florence Center
  • Indoor swimming pool - exercise room
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 764 reviews  Read Recent Reviews

  • 3.9 miles Homewood Suites by Hilton Civic Center Florence
    3450 West Radio Drive, Florence, SC 29501
    3.9 miles from I-95 at US 52, Exit 164
    From $139
    Enter Dates
    Homewood Suites by Hilton Civic Center Florence

    Check In15 00
    Check Out12 00

    Rated Very High
  • Upscale, smoke-free, all-suite, extended-stay hotel
  • Near I-95 at I-20 and Florence Center
  • Indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 121 reviews  Read Recent Reviews

  • 4.0 miles Holiday Inn Express Hotel & Suites Civic Center Florence
    3440 West Radio Drive, I-20, Exit 141, Florence, SC 29501
    4.0 miles from I-95 at US 52, Exit 164
    From $114
    Enter Dates
    Holiday Inn Express Hotel & Suites Civic Center Florence

    Check In15 00
    Check Out12 00

    Rated Very High
  • Midscale, smoke-free hotel near I-95 at I-20
  • Also near Florence Center
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 503 reviews  Read Recent Reviews

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Nearby Attractions


Hotels near Highway 52 Florence   0.3 mile SE
Hotels near Florence Federal Building   2.7 miles SE
Hotels near Downtown Florence   2.8 miles SE
Hotels near Sexton Dental Clinic   2.9 miles SE
Hotels near McLeod Regional Medical Center   3.2 miles SE
Hotels near Magnolia Mall   3.3 miles SW
Hotels near Florence Center   3.8 miles SW
Hotels near Florence Airport – FLO   4.6 miles SE
Hotels near Darlington Raceway   8 miles NW
Hotels near Francis Marion University   9 miles east
Hotels near Coker College   18 miles NW
Hotels near Robinson Nuclear Plant   24 miles NW

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How Do We Order Hotels?

We order the hotels on this page by how close they are to this attraction.

Most of our competitors order these same hotels in other ways that make them more money.
How Do We Define Motel?

To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.

At hotels, on the other hand, you can enter your room only through a hall inside the building.
Florence Hotel Tips

Important Hotel Tips


Florence Hotels, Motels, Lodging, and Accommodations near I-95 at US 52, Exit 164 – Florence, South Carolina SC, USA

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