25 Hotels TRULY CLOSEST to Highway 52 Florence, SC | HotelGuides.com
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HotelGuides.com > South Carolina > Florence > Hotels near Highway 52

Hotels and Motels near Highway 52 – Florence, SC


Use this guide to find hotels and motels near Highway 52 in Florence, South Carolina. In Florence, Highway 52 is also called West Lucas Street.

If you need help finding a hotel that is open, call us at 1-800-916-4526.
Map of Hotels and Motels near Highway 52 Florence
 

Hotels closest to Highway 52 Florence

Rates shown below are averages. Click See Rates to see rates for your dates.
  • Super 8 Hotel Florence

    1832 1/2 West Lucas Street, Florence, SC 29501

    Enter Dates
    Super 8 Hotel Florence

    Check In1400
    Check Out1100

    Rated Average
    • Cheap motel near I-95 at US 52
    • Outdoor swimming pool open in summer
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 412 reviews  Read Recent Reviews

  • Best Western Inn Florence

    1808 West Lucas Street, Florence, SC 29501

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    Best Western Inn Florence

    Check In1500
    Check Out1100

    Rated Average
    • Midscale motel near I-95 at US 52
    • Outdoor swimming pool open in summer
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 503 reviews  Read Recent Reviews

  • Baymont Inn & Suites Florence

    1826 West Lucas Street, Florence, SC 29501

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    Baymont Inn & Suites Florence

    Check In15 00
    Check Out11 00

    Rated Average
    • Midscale, smoke-free motel near I-95 at US 52
    • Outdoor swimming pool open in summer - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    Not pet friendly - no pets allowed. - Oct 2015
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 1857 reviews  Read Recent Reviews

  • Knights Inn Florence

    1834 West Lucas Street, Florence, SC 29501

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    Knights Inn Florence

    Check In1500
    Check Out1100

    Rated Very Low – Not Recommended
    • Cheap, smoke-free motel near I-95 at US 52
    • Single-story, 109 rooms
    • Outdoor swimming pool open in summer
    • Free WiFi
    • Free parking - truck parking
    Pet friendly motel More >
    TripAdvisor Traveler Rating:  2.0 of 5 stars
    Based on 92 reviews  Read Recent Reviews

  • Econo Lodge Florence

    1920 West Lucas Street, Florence, SC 29501

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    Econo Lodge Florence

    Check In14 00
    Check Out11 00

    Rated Low – Not Recommended
    • Cheap motel near I-95 at US 52
    • Some smoking rooms
    • Outdoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 247 reviews  Read Recent Reviews

  • Comfort Suites Florence

    2120 West Lucas Street, Florence, SC 29501

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    Comfort Suites Florence

    Check In15 00
    Check Out11 00

    Rated High
    • Midscale, smoke-free, all-suite hotel
    • Near I-95 at US 52
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 535 reviews  Read Recent Reviews

  • Country Inn & Suites by Radisson Florence

    1739 Mandeville Road, Florence, SC 29501

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    Country Inn & Suites by Radisson Florence

    Check In15 00
    Check Out12 00

    Rated High
    • Upper-midscale, smoke-free hotel near I-95 at US 52
    • Outdoor swimming pool open in summer - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jun 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 901 reviews  Read Recent Reviews

  • Park Inn Florence

    1729 Mandeville Road, Florence, SC 27407

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    Park Inn Florence

    Check In15 00
    Check Out12 00

    Rated Very High
    • Midscale, smoke-free, interstate hotel near I-95 at US 52
    • Heated indoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - June 2020
    TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 28 reviews  Read Recent Reviews

  • Howard Johnson Express Inn Northwest Florence

    2038 West Lucas Street, Florence, SC 29501

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    Howard Johnson Express Inn Northwest Florence

    Check In1500
    Check Out1100

    Rated High
    • Cheap motel near I-95 at US 52
    • Outdoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    Not pet friendly - no pets allowed. - May 2019
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 496 reviews  Read Recent Reviews

  • Hampton Inn & Suites North I-95 Florence

    1735 Stokes Road, Florence, SC 29501

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    Hampton Inn & Suites North I-95 Florence

    Check In15 00
    Check Out12 00

    Rated Very High
    • Upper-midscale, smoke-free hotel near I-95 at US 52
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    Not pet friendly - no pets allowed. - Jun 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 1204 reviews  Read Recent Reviews

  • Days Inn I-95 North Florence

    2111 West Lucas Street, Florence, SC 29501

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    Days Inn I-95 North Florence

    Check In1500
    Check Out1100

    Rated Average
    • Cheap motel near I-95 at US 52
    • Outdoor swimming pool open in summer
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 928 reviews  Read Recent Reviews

  • La Quinta Inn & Suites Florence

    2123 West Lucas Street, Florence, SC 29501

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    La Quinta Inn & Suites Florence

    Check In15 00
    Check Out12 00

    Rated Average
    • Midscale, smoke-free hotel near I-95 at US 52
    • Outdoor swimming pool open in summer - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 1074 reviews  Read Recent Reviews

  • Tru by Hilton Hotel I-95 Florence

    2140 West Lucas Street, Florence, SC 29501

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    Tru by Hilton Hotel I-95 Florence

    Check In15 00
    Check Out12 00

    Rated High
    • Midscale, smoke-free hotel near I-95 at US 52
    • Indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Aug 2018
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 135 reviews  Read Recent Reviews

  • Microtel Inn & Suites by Wyndham Florence

    1912 Enterprise Drive, Florence, SC 29502

    Enter Dates
    Microtel Inn & Suites by Wyndham Florence

    Check In1500
    Check Out1100

    Rated Average
    • Cheap, smoke-free hotel near I-95 at US 52
    • No swimming pool
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jan 2020
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 319 reviews  Read Recent Reviews

  • Hotel Florence

    126 West Evans Street, Florence, SC 29501

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    Hotel Florence

    Check In16 00
    Check Out11 00

    Rated Very High
    • Upscale, smoke-free, full-service, downtown hotel
    • Near I-95 - 3 miles from Florence Airport
    • An Ascend Hotel Collection Member
    • No shuttle to Florence Airport
    • No swimming pool
    • Exercise room
    • Free WiFi
    • Free parking
    • Free park and fly up to 7 nights only
    Not pet friendly - no pets allowed. - Jun 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 551 reviews  Read Recent Reviews

  • Hyatt Place Hotel Downtown Florence

    100 East Evans Street, Florence, SC 29506

    Enter Dates
    Hyatt Place Hotel Downtown Florence

    Check In15 00
    Check Out11 00

    Rated High
    • Upscale, smoke-free, full-service, downtown hotelNear I-95
    • Outdoor swimming pool - exercise room
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 48 reviews  Read Recent Reviews

  • Red Roof Inn Florence

    2690 David McLeod Blvd, I-20, Exit 141A, Florence, SC 29501

    Enter Dates
    Red Roof Inn Florence

    Check In15 00
    Check Out11 00

    Rated Average
    • Cheap, smoke-free motel near I-95
    • Also near Florence Civic Center
    • No swimming pool
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 452 reviews  Read Recent Reviews

  • Quality Inn & Suites Civic Center Florence

    150 Dunbarton Drive, I-20, Exit 141, Florence, SC 29501

    Enter Dates
    Quality Inn & Suites Civic Center Florence

    Check In14 00
    Check Out12 00

    Rated High
    • Midscale motel near Florence Center
    • Also near I-95, I-20, and Florence Mall
    • Some smoking rooms
    • Outdoor swimming pool open in summer - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 315 reviews  Read Recent Reviews

  • Fairfield Inn & Suites by Marriott Florence

    501 Woody Jones Blvd, Florence, SC 29501

    Enter Dates
    Fairfield Inn & Suites by Marriott Florence

    Check In1600
    Check Out1100

    Rated Very High
    • Upper-midscale, smoke-free hotel near Florence Center
    • Indoor swimming pool - 24-hour exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    Not pet friendly - no pets allowed. - May 2017
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 170 reviews  Read Recent Reviews

  • Days Inn Civic Center Florence

    140 Dunbarton Drive, I-20, Exit 141, Florence, SC 29501

    Enter Dates
    Days Inn Civic Center Florence

    Check In1500
    Check Out1100

    Rated Average
    • Cheap, smoke-free motel near Florence Center
    • Also near Magnolia Mall and I-95 at I-20
    • Outdoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    Pet friendly motel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 703 reviews  Read Recent Reviews

  • Hilton Garden Inn Florence

    2671 Hospitality Blvd, Florence, SC 29501

    Enter Dates
    Hilton Garden Inn Florence

    Check In15 00
    Check Out12 00

    Rated Very High
    • Upscale, smoke-free hotel near I-95
    • Also near Florence Center
    • Heated indoor swimming pool - exercise room
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Oct 2015
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 1027 reviews  Read Recent Reviews

  • Residence Inn by Marriott Florence

    2660 Hospitality Blvd, Florence, SC 29501

    Enter Dates
    Residence Inn by Marriott Florence

    Check In1600
    Check Out1100

    Rated Very High
    • Upscale, smoke-free, all-suite, extended-stay hotel
    • Near Florence Center
    • Outdoor swimming pool open in summer
    • Exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 453 reviews  Read Recent Reviews

  • Hampton Inn & Suites Civic Center Florence

    3000 Radio Drive, Florence, SC 29501

    Enter Dates
    Hampton Inn & Suites Civic Center Florence

    Check In15 00
    Check Out12 00

    Rated Very High
    • Upper-midscale, smoke-free hotel near I-95 and civic center
    • Also near GE and Magnolia Mall
    • Outdoor swimming pool open in summer
    • Exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jun 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 617 reviews  Read Recent Reviews

  • SpringHill Suites by Marriott Florence

    2670 Hospitality Blvd, Florence, SC 29501

    Enter Dates
    SpringHill Suites by Marriott Florence

    Check In1600
    Check Out1100

    Rated Very High
    • Midscale, smoke-free, all-suite hotel near I-95
    • Also near Florence Civic Center
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    Not pet friendly - no pets allowed. - Jul 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 603 reviews  Read Recent Reviews

  • TownePlace Suites by Marriott Florence

    2650 Hospitality Blvd, Florence, SC 29501

    Enter Dates
    TownePlace Suites by Marriott Florence

    Check In1600
    Check Out1100

    Rated Very High
    • Midscale, smoke-free, all-suite, extended-stay hotel
    • Near Florence Center and I-95 at I-20
    • Outdoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 237 reviews  Read Recent Reviews

  • Courtyard by Marriott Hotel Florence

    2680 Hospitality Blvd, Florence, SC 29501

    Enter Dates
    Courtyard by Marriott Hotel Florence

    Check In1600
    Check Out1100

    Rated Very High
    • Upscale, smoke-free hotel
    • Near Florence Center
    • Heated indoor swimming pool - exercise room
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Oct 2015
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 536 reviews  Read Recent Reviews

  • Affordable Suites of America Florence

    530 Woody Jones Blvd, Florence, SC 29501

    Enter Dates
    Affordable Suites of America Florence

    Check In13 00
    Check Out11 00

    Rated Very High
    • Budget, all-suite, extended-stay motel
    • Near Florence Center
    • No swimming pool
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Dec 2015
    Note: This motel does not allow children.
    TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 40 reviews  Read Recent Reviews

  • Comfort Inn & Suites Florence

    527 Woody Jones Blvd, Florence, SC 29501

    Enter Dates
    Comfort Inn & Suites Florence

    Check In16 00
    Check Out11 00

    Rated Very High
    • Midscale, smoke-free hotel near Florence Center
    • Outdoor swimming pool open in summer - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - limited truck parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 23 reviews  Read Recent Reviews

  • Home2 Suites by Hilton Florence

    900 Woody Jones Blvd, Florence, SC 29501

    Enter Dates
    Home2 Suites by Hilton Florence

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free, all-suite, extended-stay hotel
    • Near Florence Center
    • Indoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 790 reviews  Read Recent Reviews

  • Homewood Suites by Hilton Civic Center Florence

    3450 West Radio Drive, Florence, SC 29501

    Enter Dates
    Homewood Suites by Hilton Civic Center Florence

    Check In15 00
    Check Out12 00

    Rated Very High
    • Upscale, smoke-free, all-suite, extended-stay hotel
    • Near I-95 at I-20 and Florence Center
    • Indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jun 2018
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 138 reviews  Read Recent Reviews

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Nearby Attractions


Hotels near Florence Federal Building   2.4 miles SE
Hotels near Downtown Florence   2.5 miles SE
Hotels near Sexton Dental Clinic   2.7 miles SE
Hotels near McLeod Regional Medical Center   3.0 miles SE
Hotels near Magnolia Mall   3.2 miles SW
Hotels near Florence Center   3.7 miles SW
Hotels near Florence Airport – FLO   4.4 miles SE
Hotels near Darlington Raceway   8 miles NW
Hotels near Francis Marion University   9 miles east
Hotels near Coker College   19 miles NW
Hotels near Robinson Nuclear Plant   24 miles NW

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How Do We Order Hotels?

We order the hotels on this page by how close they are to this attraction.

Most of our competitors order these same hotels in other ways that make them more money.
How Do We Define Motel?

To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.

At hotels, on the other hand, you can enter your room only through a hall inside the building.
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Hotels, Motels, Lodging, and Accommodations near Highway 52 - Florence, South Carolina SC, USA

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