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Hotels & Motels in or near Sikeston, Missouri

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Sikeston is located near the junction of I-57 and I-55 in southeastern Missouri. It is 35 miles south of Cape Girardeau and 140 miles north of Memphis, Tennessee. The hotels and motels in Sikeston are downtown and near I-55, Exit 67.

Map of Sikeston, MO Hotels and Motels
 

Hotels in or near Sikeston

Rates shown below are averages. Click See Rates to see rates for your dates.
  • Super 8 Hotel Miner Area Sikeston

    2609 East Malone, I-55, Exit 67, Sikeston, MO 63801

    Enter Dates
    Super 8 Hotel Miner Area Sikeston

    Check In1300
    Check Out1100

    Rated Average
    • Cheap hotel near Sikeston Factory Outlet Mall
    • Also near I-55
    • Some smoking rooms
    • No swimming pool
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 358 reviews  Read Recent Reviews

  • Days Inn & Suites Sikeston

    220 South Interstate Drive, I-55, Exit 67, Sikeston, MO 63801

    Enter Dates
    Days Inn & Suites Sikeston

    Check In1500
    Check Out1100

    Rated Average
    • Cheap hotel near I-55 at Hwy 62
    • 4 miles from Sikeston Jaycee Bootheel Rodeo
    • Some smoking rooms
    • Outdoor swimming pool open in summer - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 190 reviews  Read Recent Reviews

  • Best Western Plus Hotel Sikeston

    120 South Interstate Drive, Sikeston, MO 63801

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    Best Western Plus Hotel Sikeston

    Check In1500
    Check Out1100

    Rated Very High
    • Upper-midscale, smoke-free hotel near US 62 at I-55
    • This hotel is located near Sikeston Factory Outlet Mall.
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 430 reviews  Read Recent Reviews

  • Pear Tree Inn Sikeston

    2602 East Malone, I-55, Exit 67, Sikeston, MO 63801

    Enter Dates
    Pear Tree Inn Sikeston

    Check In15 00
    Check Out11 00

    Rated Very High
    • Cheap, smoke-free hotel near Sikeston Factory Outlet Mall
    • Also near I-55
    • Heated indoor-outdoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 369 reviews  Read Recent Reviews

  • Comfort Inn & Suites Sikeston

    109 Matthews Lane, I-55, Exit 67, Sikeston, MO 63801

    Enter Dates
    Comfort Inn & Suites Sikeston

    Check In14 00
    Check Out11 00

    Rated Average
    • Midscale, smoke-free hotel near I-55
    • Also near Sikeston Factory Outlet Mall
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 132 reviews  Read Recent Reviews

  • Drury Inn & Suites Sikeston

    2608 East Malone, I-55, Exit 67, Sikeston, MO 63801

    Enter Dates
    Drury Inn & Suites Sikeston

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free hotel near I-55
    • Also near Sikeston Factory Outlet Mall
    • Heated indoor-outdoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 459 reviews  Read Recent Reviews

  • Holiday Inn Express & Suites Sikeston

    115 Hospitality Drive, Sikeston, MO 63801

    Enter Dates
    Holiday Inn Express & Suites Sikeston

    Check In15 00
    Check Out11 00

    Rated High
    • Upper-midscale, smoke-free hotel near US 62 at US 60
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - March 2020
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 113 reviews  Read Recent Reviews

  • Hampton Inn Sikeston

    1240 Commerce Drive, Sikeston, MO 63801

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    Hampton Inn Sikeston

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free hotel near downtown
    • Also near US 61 at US 60
    • 92 rooms
    • Heated indoor swimming pool - 24-hour exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jan 2018
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 75 reviews  Read Recent Reviews

  • 13 miles Quality Inn Charleston

    102 Drake Street, I-57, Exit 10, Charleston, MO 63834
    13 miles

    Enter Dates
    Quality Inn Charleston

    Check In15 00
    Check Out11 00

    Rated Average
    • Midscale motel near I-57 at MO 105
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Pet friendly motel More >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 69 reviews  Read Recent Reviews

  • 15 miles Super 8 Motel Charleston

    310 South Story Street, Building A, I-57, Exit 12, Charleston, MO 63834
    15 miles

    Enter Dates
    Super 8 Motel Charleston

    Check In1500
    Check Out1100

    Rated Average
    • Cheap motel near I-57 at US 62
    • This motel is located 1.5 miles east of downtown Charleston.
    • Single-story, 60 rooms
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly motel More >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 248 reviews  Read Recent Reviews

  • 16 miles Eagle Inn Charleston

    2811 East Marshall Street, I-57, Exit 12, Charleston, MO 63834
    16 miles

    Enter Dates
    Eagle Inn Charleston

    Check In16 00
    Check Out11 00

    Rated Average
    • Cheap, highway motel near I-57 at US 62
    • 2.5 miles east of downtown Charleston
    • Single-story, 20 rooms
    • Some smoking rooms
    • No swimming pool
    • Free WiFi
    • Free parking - truck parking
    Pet friendly motel More >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 20 reviews  Read Recent Reviews

  • 22 miles Econo Lodge Dexter

    913 Outer Road, Dexter, MO 63841
    22 miles

    Enter Dates
    Econo Lodge Dexter

    Check In14 00
    Check Out11 00

    Rated Average
    • Cheap, highway hotel near downtown Dexter
    • Some smoking rooms
    • No swimming pool
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 45 reviews  Read Recent Reviews

  • 22 miles Travelodge Dexter

    1608 West Business US 60, Dexter, MO 63841
    22 miles

    Enter Dates
    Travelodge Dexter

    Check In1500
    Check Out1200

    Rated Very Low – Not Recommended
    • Cheap, smoke-free motel near Heritage House
    • No swimming pool
    • Exercise room
    • Free WiFi
    • Free parking
    Pet friendly motel More >
    TripAdvisor Traveler Rating:  2.5 of 5 stars
    Based on 42 reviews  Read Recent Reviews

  • 24 miles Quality Inn Cairo

    13201 Kessler Road, Cairo, IL 62914
    24 miles

    Enter Dates
    Quality Inn Cairo

    Check In16 00
    Check Out11 00

    Rated Average
    • Midscale, interstate motel northwest of downtown
    • Near I-57 at US 51
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    Pet friendly motel More >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 66 reviews  Read Recent Reviews

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Sikeston Info

Pet Friendly Hotels in or near Sikeston

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Hotels near Me

Nearby Attractions


Hotels near Lambert's Cafe   2.4 miles east
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Nearby Cities


Charleston MO Hotels   13 miles east
Benton MO Hotels   15 miles north
New Madrid MO Hotels   20 miles south
Dexter MO Hotels   21 miles west
Scott City MO Hotels   24 miles north
Cairo IL Hotels   24 miles east
Marston MO Hotels   25 miles south
Cape Girardeau MO Hotels   29 miles north
How Do We Order Hotels?

On place pages like this, we order hotels from lowest cost to highest – except we list low-rated hotels at the bottom of the page.

Most of our competitors order these same hotels in other ways that make them more money.
How Do We Define Motel?

To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.

At hotels, on the other hand, you can enter your room only through a hall inside the building.
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Sikeston Hotels near Me

Sikeston Hotels, Motels, Lodging, and Accommodations – Sikeston, Missouri MO, USA

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