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Hotels & Motels in or near Sikeston, MO



Sikeston is located near the junction of I-57 and I-55 in southeastern Missouri. It is 35 miles south of Cape Girardeau and 140 miles north of Memphis, Tennessee. The hotels and motels in Sikeston are downtown and near I-55, Exit 67.

 
 Rates shown below are averages. Use Search above to see rates for your dates.
  • Super 8 Hotel Miner Area Sikeston - I-55, Exit 67

    2609 East Malone, I-55, Exit 67, Sikeston, MO 63801

    Enter Dates
    Super 8 Hotel Miner Area Sikeston - I-55, Exit 67

    Check In15 00
    Check Out11 00

    Rated Average
    • Cheap hotel near Sikeston Factory Outlet Mall
    • Also near I-55, Exit 67
    • 2 floors, 63 rooms and suites - no elevator
    • Some smoking rooms
    • No swimming pool
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
  • Pet friendly hotel More >
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 372 reviews  Read Recent Reviews

  • Days Inn & Suites Sikeston - I-55, Exit 67

    220 South Interstate Drive, I-55, Exit 67, Sikeston, MO 63801

    Enter Dates
    Days Inn & Suites Sikeston - I-55, Exit 67

    Check In15 00
    Check Out11 00

    Rated Average
    • Cheap hotel near I-55 at Hwy 62
    • 4 miles from Sikeston Jaycee Bootheel Rodeo
    • 2 floors, 60 rooms and suites - elevator
    • Some smoking rooms
    • Outdoor swimming pool open in summer - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
  • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 220 reviews  Read Recent Reviews

  • Best Western Plus Sikeston Hotel

    120 South Interstate Drive, Sikeston, MO 63801

    Enter Dates
    Best Western Plus Sikeston Hotel

    Check In1500
    Check Out1100

    Rated Average
    • Upper-midscale, smoke-free hotel near US 62 at I-55
    • Near Sikeston Factory Outlet Mall
    • 2 floors, 55 rooms - elevator
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
  • Pet friendly hotel More >
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 466 reviews  Read Recent Reviews

  • Pear Tree Inn Sikeston - I-55, Exit 67

    2602 East Malone, I-55, Exit 67, Sikeston, MO 63801

    Enter Dates
    Pear Tree Inn Sikeston - I-55, Exit 67

    Check In15 00
    Check Out11 00

    Rated Very High
    • Cheap, smoke-free hotel
    • Near I-55 and Sikeston Factory Outlet Mall
    • 4 floors, 80 rooms and suites
    • Heated indoor-outdoor swimming pool
    • Exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
  • Pet friendly hotel More >
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 397 reviews  Read Recent Reviews

  • Comfort Inn & Suites Sikeston - I-55, Exit 67

    109 Matthews Lane, I-55, Exit 67, Sikeston, MO 63801

    Enter Dates
    Comfort Inn & Suites Sikeston - I-55, Exit 67

    Check In14 00
    Check Out11 00

    Rated Average
    • Midscale, smoke-free hotel near I-55
    • Also near Sikeston Factory Outlet Mall
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
  • Pet friendly hotel More >
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 136 reviews  Read Recent Reviews

  • Drury Inn & Suites Sikeston - I-55, Exit 67

    2608 East Malone, I-55, Exit 67, Sikeston, MO 63801

    Enter Dates
    Drury Inn & Suites Sikeston - I-55, Exit 67

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free hotel near I-55
    • Also near Sikeston Factory Outlet Mall
    • 5 floors, 154 rooms and suites
    • Heated indoor-outdoor swimming pool - exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
  • Pet friendly hotel More >
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 477 reviews  Read Recent Reviews

  • Holiday Inn Express & Suites Sikeston

    115 Hospitality Drive, Sikeston, MO 63801

    Enter Dates
    Holiday Inn Express & Suites Sikeston

    Check In15 00
    Check Out11 00

    Rated High
    • Upper-midscale, smoke-free hotel near US 62 at US 60
    • 3 floors, 73 rooms and suites - elevator
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
  • Not pet friendly - no pets allowed. - March 2020
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 121 reviews  Read Recent Reviews

  • Hampton Inn Sikeston

    1240 Commerce Drive, Sikeston, MO 63801

    Enter Dates
    Hampton Inn Sikeston

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free hotel near downtown
    • Also near US 61 at US 60
    • 4 floors, 92 rooms
    • Heated indoor swimming pool
    • 24-hour exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
  • Pet friendly hotel More >
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 111 reviews  Read Recent Reviews

  • 13 miles Quality Inn Charleston - I-57, Exit 10

    102 Drake Street, I-57, Exit 10, Charleston, MO 63834
    13 miles to Sikeston

    Enter Dates
    Quality Inn Charleston - I-57, Exit 10

    Check In15 00
    Check Out11 00

    Rated Average
    • Midscale motel near I-57 at MO 105
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking
  • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 77 reviews  Read Recent Reviews

  • 15 miles Super 8 Motel Charleston - I-57, Exit 12

    310 South Story Street, Building A, I-57, Exit 12, Charleston, MO 63834
    15 miles to Sikeston

    Enter Dates
    Super 8 Motel Charleston - I-57, Exit 12

    Check In1500
    Check Out1100

    Rated Average
    • Cheap motel near I-57 at US 62
    • This motel is located 1.5 miles east of downtown Charleston.
    • Single-story, 60 rooms
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
  • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 268 reviews  Read Recent Reviews

  • 16 miles Eagle Inn Charleston - I-57, Exit 12

    2811 East Marshall Street, I-57, Exit 12, Charleston, MO 63834
    16 miles to Sikeston

    Enter Dates
    Eagle Inn Charleston - I-57, Exit 12

    Check In16 00
    Check Out11 00

    Rated Average
    • Cheap, highway motel near I-57 at US 62
    • 2.5 miles east of downtown Charleston
    • Single-story, 20 rooms
    • Some smoking rooms
    • No swimming pool
    • Microwave and refrigerator in every room
    • Free WiFi
    • Free parking - truck parking
  • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 22 reviews  Read Recent Reviews

  • 22 miles Econo Lodge Dexter

    913 Outer Road, Dexter, MO 63841
    22 miles to Sikeston

    Enter Dates
    Econo Lodge Dexter

    Check In14 00
    Check Out11 00

    Rated Average
    • Cheap, highway hotel near downtown Dexter
    • 2 floors, 40 rooms - no elevator
    • Some smoking rooms
    • No swimming pool
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking
  • Pet friendly hotel More >
  • Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 46 reviews  Read Recent Reviews

  • 22 miles Travelodge Dexter

    1608 West Business US 60, Dexter, MO 63841
    22 miles to Sikeston

    Enter Dates
    Travelodge Dexter

    Check In1500
    Check Out1200

    Rated Very Low – Not Recommended
    • Cheap, smoke-free motel near Heritage House
    • Next door to 24-hour restaurant
    • 2 floors, 123 rooms and suites - no elevator
    • No swimming pool
    • Exercise room
    • Free WiFi
    • Free parking
  • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  2.5 of 5 stars
    Based on 49 reviews  Read Recent Reviews

  • 24 miles Quality Inn Cairo - I-57, Exit 1

    13201 Kessler Road, I-57, Exit 1, Cairo, IL 62914
    24 miles to Sikeston

    Enter Dates
    Quality Inn Cairo - I-57, Exit 1

    Check In16 00
    Check Out11 00

    Rated Average
    • Midscale, interstate motel northwest of downtown
    • Near I-57 at US 51
    • 2 floors, 38 rooms - no elevator
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
  • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 68 reviews  Read Recent Reviews

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Sikeston Info

Pet Friendly Hotels in or near Sikeston

Sikeston Group Hotel Rates

Hotels near Me

Nearby Attractions


Hotels near Lambert's Cafe   2.4 miles east
Hotels near Mound City National Cemetery   27 miles NE

Nearby Cities


New Madrid MO Hotels   20 miles south
Dexter MO Hotels   21 miles west
Scott City MO Hotels   24 miles north
Marston MO Hotels   25 miles south
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How Do We Order Hotels?

On place pages like this, we order hotels from lowest cost to highest – except we list low-rated hotels at the bottom of the page.

Most of our competitors order these same hotels in other ways that make them more money.
How Do We Define Motel?

To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.

At hotels, on the other hand, you can enter your room only through a hall inside the building.
Book Group Reservations
Hotel Booking Tips
  1. Beware of non-refundable reservations that could cost you a lot of money if you change or cancel them. +Non-refundable reservations are a gamble that will usually save you less than $10. If you make a $90 non-refundable reservation instead of a $100 refundable booking, you are betting $90 to win $10. Would you do that in Las Vegas?
  2. Don't assume you can cancel a non-refundable reservation without penalty if you notify the hotel weeks or even months in advance. +Often you cannot – because some hotels' profit strategy is to get paid more than once for the same room for the same night.
  3. Always read cancellation policies carefully before you make a reservation. + When is the latest date and time you can cancel without penalty?
    More >
  4. When you make a reservation, you will receive a confirmation email. Take a copy with you to the hotel.
  5. The earlier in the afternoon you check into a hotel, the more likely you will get a room or suite that matches your preferences.



Sikeston Hotels, Motels, Lodging, and Accommodations – Sikeston, Missouri MO, USA

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