From West to East
I-64 begins at I-70 in Wentzville, Missouri.
O'Fallon Hotels on I-64 – MO Highway K, Exit 9
Weldon Spring Hotels on I-64 – Exits 10, 11
Chesterfield Hotels on I-64 – Exits 14, 17, 19
Town and Country Hotels on I-64 – MO 141, Exit 22
St Louis Hotels on I-64 Exits 28A, 31B, 33C, 34B, 36A, 38, 39, 40
The closest hotels on I-64 east of St Louis are in Caseyville, Illinois.
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Hotels on I-64
Missouri Hotels on I-64
Illinois Hotels on I-64
Indiana Hotels on I-64
Kentucky Hotels on I-64
West Virginia Hotels on I-64
Virginia Hotels on I-64
Map of Missouri I-64 Hotels
On place pages like this, we order hotels from lowest cost to highest except we list low-rated hotels at the bottom of the page.
Most of our competitors order these same hotels in other ways that make them more money.
To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.
At hotels, on the other hand, you can enter your room only through a hall inside the building.