The closest hotels on I-5 northwest of Los Angeles are in Sylmar, California.
I-5 runs on the eastern edge of Los Angeles. Most of the Los Angeles hotels are west of I-5. These exits provide the closest I-5 interstate hotels to Los Angeles.
Burbank Hotels I-5 at Exits 146A, 148, and 149
Commerce Hotels I-5 at Exits 126, 128, and 129
Visit our guide to all Los Angeles hotels to find the best hotel for you.
The closest I-5 hotels southeast of Los Angeles are in Pico Rivera, California.