Hotels and Motels near I-22

From West to East – Byhalia, MS to Birmingham, AL

Mississippi Hotels on I-22

The western terminus of I-22 is at I-269 near Byhalia, Mississippi.

Byhalia Hotels on I-22 – MS 309, Exit 14

Holly Springs Hotels on I-22 – MS 7, Exit 30

New Albany Hotels on I-22 – MS 30, Exit 61

Tupelo Hotels on I-22 – Exits 81, 85, 86A, 87 – near McCullough Blvd

Fulton Hotels on I-22 – MS 25, Exit 104

The closest I-22 hotels east of Fulton are in Hamilton, Alabama.

Alabama Hotels on I-22

The closest I-22 hotels west of Hamilton are in Fulton, Mississippi.

Hamilton Hotels on I-22 – US 278, Exit 16

Guin Hotels on I-22 – AL 44, Exit 26

Winfield Hotels on I-22 – AL 129, Exit 30

Jasper Hotels on I-22 – Exits 57, 65

The western terminus of I-22 is at I-65 near Birmingham, Alabama.

HotelGuides was very helpful. It was hassle free and I found a room at a great price when I needed it.

- Melissa Rigsby

Why Book Here?
- Pay at hotel
- Live Agents
- Lowest price
- All Room Types Available
- Group Rates
See more reasons

Hotels on US Interstates

I-4 Hotels

I-5 Hotels

I-10 Hotels

I-15 Hotels

I-20 Hotels

I-24 Hotels

I-25 Hotels

I-26 Hotels

I-29 Hotels

I-30 Hotels

I-35 Hotels

I-39 Hotels

I-40 Hotels

I-44 Hotels

I-45 Hotels

I-49 Hotels

I-55 Hotels

I-57 Hotels

I-59 Hotels

I-64 Hotels

I-65 Hotels

I-69 Hotels

I-70 Hotels

I-71 Hotels

I-74 Hotels

I-75 Hotels

I-76 Hotels

I-77 Hotels

I-79 Hotels

I-80 Hotels

I-81 Hotels

I-84 Hotels

I-85 Hotels

I-87 Hotels

I-90 Hotels

I-94 Hotels

I-95 Hotels

All US Interstate Hotels

How Do We Order Hotels?

How Do We Define Motel?

To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.

At hotels, on the other hand, you can enter your room only through a hall inside the building.

Hotel Booking Tips

Beware of non-refundable reservations that could cost you a lot of money if you change or cancel them. +Non-refundable reservations are a gamble that will usually save you less than $10. If you make a $90 non-refundable reservation instead of a $100 refundable booking, you are betting $90 to win $10. Would you do that in Las Vegas? -
Don't assume you can cancel a non-refundable reservation without penalty if you notify the hotel weeks or even months in advance. +Often you cannot – because some hotels' profit strategy is to get paid more than once for the same room for the same night. -
Always read cancellation policies carefully before you make a reservation. + When is the latest date and time you can cancel without penalty? -
More >
When you make a reservation, you will receive a confirmation email. Take a copy with you to the hotel.
The earlier in the afternoon you check into a hotel, the more likely you will get a room or suite that matches your preferences.