Hotels between Des Moines and Iowa City are located along I-80. Iowa City is 115 miles east of Des Moines.
From West to East
Des Moines Hotels on I-80 Exits 131, 137
Altoona Hotels on I-80 Exits 141, 142, 143
Colfax Hotels on I-80 IA 117, Exit 155
Newton Hotels on I-80 Exits 164, 168
Grinnell Hotels on I-80 West Street South, Exit 182
Williamsburg Hotels on I-80 Exits 220, 225
Iowa City Hotels on I-80 Exits 240, 242, 246, 254
Why Book Here?
- We add no fees.
- Lowest price guarantee
- Pay at hotel in most cases
- If you don't like your hotel,
we'll refund your money.
- Cash rewards + hotel points too
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All I-80 Hotels
I-80 Hotels in Iowa
Map of Iowa I-80 Hotels
Hotels near Me
On place pages like this, we order hotels from lowest cost to highest except we list low-rated hotels at the bottom of the page.
Most of our competitors order these same hotels in other ways that make them more money.
To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.
At hotels, on the other hand, you can enter your room only through a hall inside the building.