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Hotels in or near Cairo, Illinois


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Map of Cairo, IL Hotels and Motels
 

    Hotels in or near Cairo

    Rates shown below are averages. Click See Rates to see rates for your dates.
  • Quality Inn Cairo
    13201 Kessler Road, Cairo, IL 62914

    From $101
    Enter Dates
    Quality Inn Cairo

    Check In16 00
    Check Out11 00

    Rated Average
  • Midscale, interstate motel northwest of downtown
  • Near I-57 at US 51
  • Outdoor swimming pool open in summer
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 65 reviews  Read Recent Reviews

  • 9 miles Eagle Inn Charleston
    2811 East Marshall Street, I-57, Exit 12, Charleston, MO 63834
    9 miles from Cairo
    From $83
    Enter Dates
    Eagle Inn Charleston

    Check In16 00
    Check Out11 00

    Rated Average
  • Cheap, highway motel near I-57 at US 62
  • 2.5 miles east of downtown Charleston
  • Single-story, 20 rooms
  • No swimming pool
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 20 reviews  Read Recent Reviews

  • 10 miles Super 8 Hotel Charleston
    310 South Story Street, Building A, I-57, Exit 12, Charleston, MO 63834
    10 miles from Cairo
    From $58
    Enter Dates
    Super 8 Hotel Charleston

    Check In1500
    Check Out1100

    Rated Average
  • Cheap motel near I-57 at US 62
  • This motel is located 1.5 miles east of downtown Charleston.
  • Single-story, 60 rooms
  • Outdoor swimming pool open in summer
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Pet friendly motel More >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 246 reviews  Read Recent Reviews

  • 12 miles Quality Inn Charleston
    102 Drake Street, I-57, Exit 10, Charleston, MO 63834
    12 miles from Cairo
    From $63
    Enter Dates
    Quality Inn Charleston

    Check In15 00
    Check Out11 00

    Rated Average
  • Midscale motel near I-57 at MO 105
  • Outdoor swimming pool open in summer
  • Free continental breakfast
  • Free WiFi
  • Free parking
  • Pet friendly motel More >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 67 reviews  Read Recent Reviews

  • 21 miles Best Western Plus Hotel Sikeston
    120 South Interstate Drive, Sikeston, MO 63801
    21 miles from Cairo
    From $67
    Enter Dates
    Best Western Plus Hotel Sikeston

    Check In1500
    Check Out1100

    Rated Very High
  • Upper-midscale, smoke-free hotel near US 62 at I-55
  • This hotel is located near Sikeston Factory Outlet Mall.
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 415 reviews  Read Recent Reviews

  • 21 miles Days Inn & Suites Sikeston
    220 South Interstate Drive, I-55, Exit 67, Sikeston, MO 63801
    21 miles from Cairo
    From $57
    Enter Dates
    Days Inn & Suites Sikeston

    Check In1500
    Check Out1100

    Rated Average
  • Cheap hotel near I-55 at Hwy 62
  • 4 miles from Sikeston Jaycee Bootheel Rodeo
  • Some smoking rooms
  • Outdoor swimming pool open in summer - exercise room
  • Free continental breakfast
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 188 reviews  Read Recent Reviews

  • 21 miles Drury Inn & Suites Sikeston
    2608 East Malone, I-55, Exit 67, Sikeston, MO 63801
    21 miles from Cairo
    From $95
    Enter Dates
    Drury Inn & Suites Sikeston

    Check In15 00
    Check Out11 00

    Rated Very High
  • Midscale, smoke-free hotel near I-55
  • Also near Sikeston Factory Outlet Mall
  • Heated indoor-outdoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 449 reviews  Read Recent Reviews

  • 21 miles Super 8 Hotel Miner Area Sikeston
    2609 East Malone, I-55, Exit 67, Sikeston, MO 63801
    21 miles from Cairo
    From $55
    Enter Dates
    Super 8 Hotel Miner Area Sikeston

    Check In1300
    Check Out1100

    Rated Average
  • Cheap hotel near Sikeston Factory Outlet Mall
  • Also near I-55
  • No swimming pool
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 357 reviews  Read Recent Reviews

  • 21 miles Comfort Inn & Suites Sikeston
    109 Matthews Lane, I-55, Exit 67, Sikeston, MO 63801
    21 miles from Cairo
    From $91
    Enter Dates
    Comfort Inn & Suites Sikeston

    Check In14 00
    Check Out11 00

    Rated Average
  • Midscale, smoke-free hotel near I-55
  • Also near Sikeston Factory Outlet Mall
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 131 reviews  Read Recent Reviews

  • 21 miles Pear Tree Inn by Drury Sikeston
    2602 East Malone, I-55, Exit 67, Sikeston, MO 63801
    21 miles from Cairo
    From $85
    Enter Dates
    Pear Tree Inn by Drury Sikeston

    Check In15 00
    Check Out11 00

    Rated Very High
  • Midscale hotel near Sikeston Factory Outlet Mall
  • Also near I-55
  • Heated indoor-outdoor swimming pool - exercise room
  • Free continental breakfast
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 360 reviews  Read Recent Reviews

  • 25 miles Holiday Inn Express Hotel & Suites Sikeston
    115 Hospitality Drive, Sikeston, MO 63801
    25 miles from Cairo
    From $129
    Enter Dates
    Holiday Inn Express Hotel & Suites Sikeston

    Check In15 00
    Check Out11 00

    Rated High
  • Midscale, smoke-free hotel near US 62 at US 60
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 108 reviews  Read Recent Reviews

  • 25 miles Hampton Inn Sikeston
    1240 Commerce Drive, Sikeston, MO 63801
    25 miles from Cairo
    From $130
    Enter Dates
    Hampton Inn Sikeston

    Check In15 00
    Check Out11 00

    Rated Very High
  • Midscale, smoke-free hotel near downtown
  • Also near US 61 at US 60
  • 92 rooms
  • Heated indoor swimming pool - 24-hour exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 69 reviews  Read Recent Reviews

  • 26 miles Baymont Inn & Suites Metropolis
    203 East Front Street, Metropolis, IL 62960
    26 miles from Cairo
    From $50
    Enter Dates
    Baymont Inn & Suites Metropolis

    Check In1500
    Check Out1200

    Rated Very Low – Not Recommended
  • Midscale, smoke-free, downtown Metropolis hotel
  • Near Harrah's Casino - 2 miles from Fort Massac State Park
  • Heated indoor swimming pool - exercise room
  • Free continental breakfast
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 633 reviews  Read Recent Reviews

  • 27 miles Econo Lodge Paducah
    5120 Hinkleville Road, I-24, Exit 4, Paducah, KY 42001
    27 miles from Cairo
    From $45
    Enter Dates
    Econo Lodge Paducah

    Check In15 00
    Check Out11 00

    Rated Very Low – Not Recommended
  • Cheap motel near Kentucky Oaks Mall and I-24
  • Outdoor swimming pool open in summer
  • Free continental breakfast
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly motel More >
    TripAdvisor Traveler Rating:  2.5 of 5 stars
    Based on 62 reviews  Read Recent Reviews

  • 28 miles Baymont Inn & Suites Paducah
    5300 Cairo Road, I-24, Exit 3, Paducah, KY 42001
    28 miles from Cairo
    From $54
    Enter Dates
    Baymont Inn & Suites Paducah

    Check In1500
    Check Out1200

    Rated Average
  • Midscale hotel near Kentucky Oaks Mall and I-24
  • Some smoking rooms
  • No swimming pool
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking - truck parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 391 reviews  Read Recent Reviews

  • 28 miles Quality Suites Paducah
    2880 James Sanders Blvd, I-24, Exit 4, Paducah, KY 42001
    28 miles from Cairo
    From $46
    Enter Dates
    Quality Suites Paducah

    Check In15 00
    Check Out11 00

    Rated High
  • Midscale, smoke-free, all-suite hotel
  • Near US 60 and I-24
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 302 reviews  Read Recent Reviews

  • 28 miles Country Inn & Suites by Radisson Paducah
    145 McBride Lane, I-24, Exit 4, Paducah, KY 42001
    28 miles from Cairo
    From $68
    Enter Dates
    Country Inn & Suites by Radisson Paducah

    Check In15 00
    Check Out12 00

    Rated Average
  • Midscale hotel near I-24 at US 60
  • Also near Kentucky Oaks Mall
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 618 reviews  Read Recent Reviews

  • 28 miles Pear Tree Inn Paducah
    5006 Hinkleville Road, I-24, Exit 4, Paducah, KY 42001
    28 miles from Cairo
    From $75
    Enter Dates
    Pear Tree Inn Paducah

    Check In15 00
    Check Out11 00

    Rated Very High
  • Midscale, interstate motel near I-24 at US 60
  • Also near Kentucky Oaks Mall
  • Outdoor swimming pool open in summer
  • Free continental breakfast
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 203 reviews  Read Recent Reviews

  • 28 miles Super 8 Hotel Paducah
    5001 Hinkleville Road, I-24, Exit 4, Paducah, KY 42001
    28 miles from Cairo
    From $59
    Enter Dates
    Super 8 Hotel Paducah

    Check In1400
    Check Out1100

    Rated Average
  • Cheap motel near US 60 at I-24
  • Also near Kentucky Oaks Mall
  • No swimming pool
  • Free continental breakfast
  • Free WiFi
  • Free parking
  • Not pet friendly - no pets allowed.
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 441 reviews  Read Recent Reviews

  • 28 miles Drury Suites Paducah
    2930 James Sanders Blvd, I-24, Exit 4, Paducah, KY 42001
    28 miles from Cairo
    From $105
    Enter Dates
    Drury Suites Paducah

    Check In15 00
    Check Out11 00

    Rated Very High
  • Midscale, smoke-free hotel near US 60 at I-24
  • Heated indoor swimming pool - exercise room
  • Free hot breakfast buffet
  • Free WiFi
  • Free parking
  • Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >

    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 451 reviews  Read Recent Reviews

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Cairo Info

Pet Friendly Hotels in or near Cairo

Cairo Group Hotel Rates

Hotels near Me

Nearby Attractions


Hotels near Barkley Paducah – PAH   23 miles east
Hotels near Harrah's Metropolis Casino   26 miles NE
Hotels near Houck Stadium   29 miles NW
Hotels near Southeast Missouri State University   29 miles NW
Hotels near Show Me Center   29 miles NW
Earn Cash Rewards plus Hotel Reward Points

Nearby Cities


Charleston MO Hotels   11 miles SW
Ullin IL Hotels   19 miles north
Sikeston MO Hotels   24 miles west
Metropolis IL Hotels   28 miles east
Cape Girardeau MO Hotels   29 miles NW
How Do We Order Hotels?

On place pages like this, we order hotels from lowest cost to highest – except we list low-rated hotels at the bottom of the page.

Most of our competitors order these same hotels in other ways that make them more money.
How Do We Define Motel?

To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.

At hotels, on the other hand, you can enter your room only through a hall inside the building.
Hotel Tips

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Cairo Hotels near Me

Cairo Hotels, Motels, Lodging, and Accommodations – Cairo, Illinois IL Ill, USA

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