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Hotels near Jacksonville Mayo Clinic – Florida


The hotels below are listed in order of their distance from Jacksonville Mayo Clinic.

Visiting the Jacksonville Mayo Clinic in Jacksonville, FL? Then use this simple form to find nearby hotels, motels, and other lodging.

Jacksonville Mayo Clinic is located 30 miles south of the Jacksonville Airport.

If you need help finding a hotel that is open, call us at 1-800-916-4526.
Address: 4500 San Pablo Road, Jacksonville, FL 32224
Map of Hotels and Motels near Jacksonville Mayo Clinic
 

Hotels closest to Jacksonville Mayo Clinic

Rates shown below are averages. Click See Rates to see rates for your dates.
  • 0.2 mile Courtyard by Marriott Hotel Mayo Clinic Jacksonville

    14390 Mayo Blvd, Jacksonville, FL 32224
    0.2 mile from Jacksonville Mayo Clinic

    Enter Dates
    Courtyard by Marriott Hotel Mayo Clinic Jacksonville

    Check In1600
    Check Out1200

    Rated High
    • Upscale, smoke-free hotel
    • Near Mayo Clinic Florida
    • Free 24-hour shuttle to Mayo Clinic
    • Outdoor swimming pool - exercise room
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Feb 2015
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 316 reviews  Read Recent Reviews

  • 1.6 miles Holiday Inn Express & Suites Mayo Clinic Jacksonville

    4791 Windsor Commons Court, Jacksonville, FL 32224
    1.6 miles from Jacksonville Mayo Clinic

    Enter Dates
    Holiday Inn Express & Suites Mayo Clinic Jacksonville

    Check In15 00
    Check Out11 00

    Rated Average
    • Upper-midscale, smoke-free hotel
    • 3 miles west of Mayo Clinic Florida
    • Heated indoor-outdoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Dec 2019
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 195 reviews  Read Recent Reviews

  • 1.9 miles Hampton Inn & Suites Mayo Clinic Jacksonville

    13733 Beach Blvd, Jacksonville, FL 32224
    1.9 miles from Jacksonville Mayo Clinic

    Enter Dates
    Hampton Inn & Suites Mayo Clinic Jacksonville

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free hotel
    • 3 miles north of Mayo Clinic Florida
    • Free shuttle to local attractions
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jun 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 721 reviews  Read Recent Reviews

  • 2.0 miles TownePlace Suites by Marriott Mayo Clinic Jacksonville

    13741 Beach Blvd, Jacksonville, FL 32224
    2.0 miles from Jacksonville Mayo Clinic

    Enter Dates
    TownePlace Suites by Marriott Mayo Clinic Jacksonville

    Check In1500
    Check Out1100

    Rated Very High
    • Midscale, smoke-free, all-suite, extended-stay hotel
    • 3 miles north of Mayo Clinic Florida
    • Outdoor swimming pool open all year - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 6745 reviews  Read Recent Reviews

  • 3.0 miles Holiday Inn Express Jacksonville Beach

    1101 Beach Blvd, Jacksonville Beach, FL 32250
    3.0 miles from Jacksonville Mayo Clinic

    Enter Dates
    Holiday Inn Express Jacksonville Beach

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free, highway hotel
    • In downtown Jacksonville Beach
    • Heated outdoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 560 reviews  Read Recent Reviews

  • 3.0 miles Hampton Inn Marsh Landing Jacksonville Beach

    1220 Marsh Landing Parkway, Jacksonville Beach, FL 32250
    3.0 miles from Jacksonville Mayo Clinic

    Enter Dates
    Hampton Inn Marsh Landing Jacksonville Beach

    Check In15 00
    Check Out11 00

    Rated High
    • Upper-midscale, smoke-free hotel
    • 2 miles from beach - near FL 202
    • Free shuttle to Mayo Clinic
    • Outdoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jun 2019
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 953 reviews  Read Recent Reviews

  • 3.6 miles Four Points by Sheraton Hotel Beachfront Jacksonville

    11 North 1st Street, Jacksonville Beach, FL 32250
    3.6 miles from Jacksonville Mayo Clinic

    Enter Dates
    Four Points by Sheraton Hotel Beachfront Jacksonville

    Check In1600
    Check Out1100

    Rated Very High
    • Upscale, smoke-free, all-suite, oceanfront hotel
    • Heated outdoor swimming pool - 24-hour exercise room
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Note: You must be 21 or older to reserve a room at this hotel.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 1667 reviews  Read Recent Reviews

  • 3.6 miles Best Western Oceanfront Hotel Jacksonville Beach

    305 North 1st Street, Jacksonville Beach, FL 32250
    3.6 miles from Jacksonville Mayo Clinic

    Enter Dates
    Best Western Oceanfront Hotel Jacksonville Beach

    Check In1500
    Check Out1100

    Rated High
    • Midscale, smoke-free, oceanfront hotel
    • Free shuttle to Mayo Clinic
    • Outdoor swimming pool
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jun 2019
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 1355 reviews  Read Recent Reviews

  • 3.9 miles Sawgrass Marriott Golf Resort & Spa Ponte Vedra Beach

    1000 TPC Blvd, Ponte Vedra Beach, FL 32082
    3.9 miles from Jacksonville Mayo Clinic

    Enter Dates
    Sawgrass Marriott Golf Resort & Spa Ponte Vedra Beach

    Check In1600
    Check Out1100

    Rated High
    • Upper-upscale, smoke-free, full-service, golf resort
    • 6 miles from Jacksonville Beach
    • 3 heated outdoor swimming pools - exercise room
    • Full-service spa
    • Parking costs $17 per night
    Pet friendly hotel More >
    Note: This hotel charges a resort fee of $27 per night - includes WiFi.
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 1147 reviews  Read Recent Reviews

  • 3.9 miles Ponte Vedra Inn & Club Ponte Vedra Beach

    200 Ponte Vedra Blvd, Ponte Vedra Beach, FL 32082
    3.9 miles from Jacksonville Mayo Clinic

    Enter Dates
    Ponte Vedra Inn & Club Ponte Vedra Beach

    Check In16 00
    Check Out12 00

    Rated Very High
    • Luxury, smoke-free, full-service, oceanfront motel
    • Heated outdoor swimming pool - exercise room
    Not pet friendly - no pets allowed. - Jun 2015
    Note: This hotel charges a resort fee of $25 per night - includes parking and WiFi.
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 862 reviews  Read Recent Reviews

  • 4.0 miles Hampton Inn Jacksonville Beach

    1515 North 1st Street, Jacksonville Beach, FL 32250
    4.0 miles from Jacksonville Mayo Clinic

    Enter Dates
    Hampton Inn Jacksonville Beach

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free, oceanfront hotel
    • Outdoor swimming pool
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - 1 vehicle per room
    Not pet friendly - no pets allowed. - Jun 2019
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 2280 reviews  Read Recent Reviews

  • 4.0 miles Fairfield Inn & Suites by Marriott Jacksonville Beach

    1616 North First Street, Jacksonville Beach, FL 32250
    4.0 miles from Jacksonville Mayo Clinic

    Enter Dates
    Fairfield Inn & Suites by Marriott Jacksonville Beach

    Check In1500
    Check Out1100

    Rated High
    • Upper-midscale, smoke-free hotel near beach
    • Heated outdoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Sep 2015
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 288 reviews  Read Recent Reviews

  • 4.0 miles Courtyard by Marriott Hotel Jacksonville Beach

    1617 North 1st Street, Jacksonville Beach, FL 32250
    4.0 miles from Jacksonville Mayo Clinic

    Enter Dates
    Courtyard by Marriott Hotel Jacksonville Beach

    Check In1600
    Check Out1100

    Rated Very High
    • Upscale, smoke-free, oceanfront hotel
    • Heated outdoor swimming pool - exercise room
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jun 2019
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 681 reviews  Read Recent Reviews

  • 4.8 miles Holiday Inn Express & Suites Town Center Jacksonville

    10573 Brightman Blvd, Jacksonville, FL 32246
    4.8 miles from Jacksonville Mayo Clinic

    Enter Dates
    Holiday Inn Express & Suites Town Center Jacksonville

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free, interstate hotel
    • Outdoor swimming pool open all year - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jan 2020
    TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 37 reviews  Read Recent Reviews

  • 5 miles Homewood Suites by Hilton South Jacksonville

    10434 Midtown Parkway, Jacksonville, FL 32246
    5 miles from Jacksonville Mayo Clinic

    Enter Dates
    Homewood Suites by Hilton South Jacksonville

    Check In15 00
    Check Out11 00

    Rated Average
    • Upscale, smoke-free, all-suite, extended-stay hotel
    • Near University of North Florida
    • Outdoor swimming pool open in summer
    • Exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 869 reviews  Read Recent Reviews

  • 5 miles One Ocean Resort Hotel & Spa Atlantic Beach

    One Ocean Blvd, Atlantic Beach, FL 32233
    5 miles from Jacksonville Mayo Clinic

    Enter Dates
    One Ocean Resort Hotel & Spa Atlantic Beach

    Check In16 00
    Check Out12 00

    Rated High
    • Upscale, smoke-free, full-service, oceanfront hotel
    • Outdoor swimming pool - exercise room
    • Full-service spa
    • Valet parking only - $27 per night
    Pet friendly hotel More >
    Note: This hotel charges a resort fee of $27 per night - includes WiFi and snacks.
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 1437 reviews  Read Recent Reviews

  • 5 miles Lodge at Ponte Vedra Beach

    607 Ponte Vedra Blvd, Ponte Vedra Beach, FL 32082
    5 miles from Jacksonville Mayo Clinic

    Enter Dates
    Lodge at Ponte Vedra Beach

    Check In16 00
    Check Out12 00

    Rated Very High
    • Upscale, smoke-free, full-service, oceanfront resort
    • Heated outdoor swimming pool - exercise room
    Not pet friendly - no pets allowed. - Feb 2016
    Note: This hotel charges a resort fee of $29 per night - includes parking and WiFi.
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 430 reviews  Read Recent Reviews

  • 5 miles Holiday Inn Baymeadows Jacksonville

    11083 Nursery Field Drive, Jacksonville, FL 32256
    5 miles from Jacksonville Mayo Clinic

    Enter Dates
    Holiday Inn Baymeadows Jacksonville

    Check In15 00
    Check Out11 00

    Rated High
    • Upper-midscale, smoke-free hotel
    • Near University of North Florida
    • Outdoor swimming pool - exercise room
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Mar 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 320 reviews  Read Recent Reviews

  • 5 miles Hilton Garden Inn Ponte Vedra Beach

    45 TPC Blvd, Ponte Vedra Beach, FL 32082
    5 miles from Jacksonville Mayo Clinic

    Enter Dates
    Hilton Garden Inn Ponte Vedra Beach

    Check In15 00
    Check Out12 00

    Rated Very High
    • Upscale, smoke-free, full-service hotel
    • 6 miles from Jacksonville Beach
    • Outdoor swimming pool - exercise room
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Nov 2020
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 1072 reviews  Read Recent Reviews

  • 5 miles Hyatt Place Hotel South Jacksonville

    4742 Town Center Parkway, Jacksonville, FL 32246
    5 miles from Jacksonville Mayo Clinic

    Enter Dates
    Hyatt Place Hotel South Jacksonville

    Check In15 00
    Check Out12 00

    Rated Very High
    • Upscale, smoke-free hotel
    • Near University of North Florida
    • Heated outdoor swimming pool - 24-hour exercise room
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 340 reviews  Read Recent Reviews

  • 5 miles Tru by Hilton Hotel South Jacksonville

    4640 Tropea Way, Jacksonville, FL 32246
    5 miles from Jacksonville Mayo Clinic

    Enter Dates
    Tru by Hilton Hotel South Jacksonville

    Check In15 00
    Check Out12 00

    Rated High
    • Midscale, smoke-free hotel
    • Near University of North Florida
    • Outdoor swimming pool - 24-hour exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 154 reviews  Read Recent Reviews

  • 5 miles Hampton Inn Baymeadows Jacksonville

    8127 Point Meadows Drive, Jacksonville, FL 32256
    5 miles from Jacksonville Mayo Clinic

    Enter Dates
    Hampton Inn Baymeadows Jacksonville

    Check In15 00
    Check Out12 00

    Rated High
    • Upper-midscale, smoke-free hotel
    • Near University of North Florida
    • Free shuttle to local attractions
    • Outdoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Mar 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 818 reviews  Read Recent Reviews

  • 6 miles Holiday Inn Express Mayport Atlantic Beach

    2040 Mayport Road, Atlantic Beach, FL 32233
    6 miles from Jacksonville Mayo Clinic

    Enter Dates
    Holiday Inn Express Mayport Atlantic Beach

    Check In15 00
    Check Out11 00

    Rated High
    • Upper-midscale, smoke-free hotel near beach
    • 1 mile south of Mayport Naval Station
    • 10 miles from downtown Jacksonville
    • Outdoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 195 reviews  Read Recent Reviews

  • 6 miles Home2 Suites by Hilton South Jacksonville

    10715 Deerwood Park Blvd, Jacksonville, FL 32256
    6 miles from Jacksonville Mayo Clinic

    Enter Dates
    Home2 Suites by Hilton South Jacksonville

    Check In15 00
    Check Out11 00

    Rated High
    • Upper-midscale, smoke-free, all-suite, extended-stay hotel
    • Outdoor swimming pool open all year - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 71 reviews  Read Recent Reviews

  • 6 miles Candlewood Suites Atlantic Beach

    2073 Mayport Road, Atlantic Beach, FL 32233
    6 miles from Jacksonville Mayo Clinic

    Enter Dates
    Candlewood Suites Atlantic Beach

    Check In15 00
    Check Out11 00

    Rated Very High
    • Midscale, smoke-free, all-suite, extended-stay hotel
    • Outdoor swimming pool open all year - exercise room
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 1 reviews  Read Recent Reviews

  • 6 miles Extended Stay America Hotel Southside Jacksonville

    10020 Skinner Lake Drive, Jacksonville, FL 32246
    6 miles from Jacksonville Mayo Clinic

    Enter Dates
    Extended Stay America Hotel Southside Jacksonville

    Check In15 00
    Check Out11 00

    Rated Low – Not Recommended
    • Budget, smoke-free, all-suite, extended-stay motel
    • Located near University of North Florida
    • No swimming pool
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  2.5 of 5 stars
    Based on 65 reviews  Read Recent Reviews

  • 6 miles Residence Inn by Marriott Jacksonville

    10551 Deerwood Park Blvd, Jacksonville, FL 32256
    6 miles from Jacksonville Mayo Clinic

    Enter Dates
    Residence Inn by Marriott Jacksonville

    Check In1600
    Check Out1200

    Rated Average
    • Upscale, smoke-free, all-suite, extended-stay hotel
    • Near University of North Florida
    • Outdoor swimming pool open in summer - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 275 reviews  Read Recent Reviews

  • 6 miles WoodSpring Suites Southeast Jacksonville

    3425 Saland Way, Jacksonville, FL 32246
    6 miles from Jacksonville Mayo Clinic

    Enter Dates
    WoodSpring Suites Southeast Jacksonville

    Check In15 00
    Check Out11 00

    Rated Average
    • Budget, smoke-free, all-suite, extended-stay hotel
    • Near UNF
    • No swimming pool
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Note: Some WoodSpring Suites charge a weekly rate, even if you stay just one night.
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 43 reviews  Read Recent Reviews

  • 6 miles Sheraton Hotel Jacksonville

    10605 Deerwood Park Blvd, Jacksonville, FL 32256
    6 miles from Jacksonville Mayo Clinic

    Enter Dates
    Sheraton Hotel Jacksonville

    Check In1500
    Check Out1200

    Rated Very High
    • Upscale, smoke-free, full-service hotel near UNF
    • In Deerwood Park area
    • 4 miles southwest of UNF - 10 miles from beach
    • Heated indoor swimming pool - exercise room
    • Free WiFi
    • Free parking - truck parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 263 reviews  Read Recent Reviews

  • 6 miles Best Western Mayport Inn & Suites Atlantic Beach

    2389 Mayport Road, Atlantic Beach, FL 32233
    6 miles from Jacksonville Mayo Clinic

    Enter Dates
    Best Western Mayport Inn & Suites Atlantic Beach

    Check In1500
    Check Out1100

    Rated High
    • Midscale, smoke-free hotel 2 miles from Mayport Naval Station
    • Outdoor swimming pool - 24-hour exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 336 reviews  Read Recent Reviews

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Nearby Attractions


Hotels near Beach Blvd Jacksonville   1.7 miles north
Hotels near Adventure Landing Jacksonville Beach   2.4 miles NE
Hotels near Hodges Blvd Jacksonville   2.4 miles NW
Hotels near Kernan Blvd Jacksonville   3.5 miles west
Hotels near Joe's Crab Shack   3.5 miles NE
Hotels near Jacksonville Beach Pier   3.7 miles NE
Hotels near Casa Marina Hotel   3.7 miles NE
Hotels near Casa Marina   3.7 miles NE
Hotels near UNF – University of North Florida   4.0 miles west
Hotels near 1st Street Jacksonville Beach   4.1 miles NE
Oceanfront Neptune Beach in Neptune Beach   4.4 miles NE
Hotels near Topgolf Jacksonville   4.7 miles west
Hotels near St Johns Town Center   4.9 miles west
Hotels near Cheesecake Factory   5 miles west
Hotels near Players Championship   5 miles SE

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How Do We Order Hotels?

We order the hotels on this page by how close they are to this attraction.

Most of our competitors order these same hotels in other ways that make them more money.
How Do We Define Motel?

To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.

At hotels, on the other hand, you can enter your room only through a hall inside the building.
Jacksonville Hotel Tips

Important Hotel Tips




Address: 4500 San Pablo Road, Jacksonville, FL 32224 Hotels, Motels, Lodging, and Accommodations near Jacksonville Mayo Clinic, Jacksonville, Florida FL Fla, USA

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