25 Hotels TRULY CLOSEST to Sanford School of Medicine, Sioux Falls, SD | HotelGuides.com
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Hotels near Sanford School of Medicine – Sioux Falls


The hotels below are listed in order of their distance from Sanford School of Medicine.

The University of South Dakota's Sanford School of Medicine is located at the Sanford USD Medical Center near downtown Sioux Falls. Most of the closest hotels are in the downtown area.

If you need help finding a hotel that is open, call us at 1-800-916-4526.
Address: 1400 West 22nd Street, Sioux Falls, SD 57105
Map of Hotels and Motels near Sanford School of Medicine
 

Hotels closest to Sanford School of Medicine

Rates shown below are averages. Click See Rates to see rates for your dates.
  • 0.2 mile Home2 Suites by Hilton Sioux Falls

    1120 South Grange Avenue, Sioux Falls, SD 57105
    0.2 mile from Sanford School of Medicine

    Enter Dates
    Home2 Suites by Hilton Sioux Falls

    Check In15 00
    Check Out12 00

    Rated Very High
    • Upper-midscale, smoke-free, all-suite, extended-stay hotel
    • Near University of Sioux Falls
    • Heated indoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 680 reviews  Read Recent Reviews

  • 1.3 miles Hotel on Phillips Sioux Falls

    100 North Phillps Avenue, Sioux Falls, SD 57104
    1.3 miles from Sanford School of Medicine

    Enter Dates
    Hotel on Phillips Sioux Falls

    Check In15 00
    Check Out11 00

    Rated Very High
    • Midscale, smoke-free, downtown hotel
    • 3 miles from Sioux Falls Airport
    • No shuttle to Sioux Falls Airport
    • No swimming pool
    • Exercise room
    • Free WiFi
    • Valet parking only - $20 per night
    • Park and fly not allowed
    Not pet friendly - no pets allowed. - Feb 2020
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 41 reviews  Read Recent Reviews

  • 1.3 miles Holiday Inn City Centre Sioux Falls

    100 West 8th Street, Sioux Falls, SD 57104
    1.3 miles from Sanford School of Medicine

    Enter Dates
    Holiday Inn City Centre Sioux Falls

    Check In15 00
    Check Out11 00

    Rated High
    • Upper-midscale, smoke-free hotel
    • Located in downtown Sioux Falls
    • Free shuttle to Sioux Falls Airport
    • Heated indoor swimming pool - exercise room
    • Internet access costs $10 per night
    • Parking costs $5 per night
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 927 reviews  Read Recent Reviews

  • 1.4 miles Hilton Garden Inn Downtown Sioux Falls

    201 East 8th Street, Sioux Falls, SD 57103
    1.4 miles from Sanford School of Medicine

    Enter Dates
    Hilton Garden Inn Downtown Sioux Falls

    Check In15 00
    Check Out12 00

    Rated High
    • Upscale, smoke-free, full-service, riverview hotel
    • In downtown Sioux Falls - overlooks Big Sioux River
    • Free 24-hour shuttle to Sioux Falls Airport
    • Indoor swimming pool - 24-hour exercise room
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Oct 2015
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 720 reviews  Read Recent Reviews

  • 1.4 miles Country Inn & Suites by Radisson Sioux Falls

    200 East 8th Street, Sioux Falls, SD 57104
    1.4 miles from Sanford School of Medicine

    Enter Dates
    Country Inn & Suites by Radisson Sioux Falls

    Check In15 00
    Check Out12 00

    Rated High
    • Upper-midscale, smoke-free, downtown Sioux Falls hotel
    • Heated indoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jan 2015
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 700 reviews  Read Recent Reviews

  • 1.7 miles ClubHouse Hotel & Suites Sioux Falls

    2320 South Louise Avenue, Sioux Falls, SD 57106
    1.7 miles from Sanford School of Medicine

    Enter Dates
    ClubHouse Hotel & Suites Sioux Falls

    Check In15 00
    Check Out11 00

    Rated Very High
    • Midscale, smoke-free hotel near Empire Mall
    • Free shuttle to Sioux Falls Airport
    • Heated indoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 434 reviews  Read Recent Reviews

  • 1.7 miles Ramada Hotel Sioux Falls

    407 South Lyons Avenue, I-29, Exit 79, Sioux Falls, SD 57106
    1.7 miles from Sanford School of Medicine

    Enter Dates
    Ramada Hotel Sioux Falls

    Check In1500
    Check Out1100

    Rated Low – Not Recommended
    • Midscale hotel near Great Plains Zoo
    • Also near I-29 and WH Lyon Fairgrounds
    • Some smoking rooms
    • Heated indoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 525 reviews  Read Recent Reviews

  • 1.8 miles Holiday Inn Express & Suites Empire Mall Sioux Falls

    2501 South Shirley Avenue, Sioux Falls, SD 57106
    1.8 miles from Sanford School of Medicine

    Enter Dates
    Holiday Inn Express & Suites Empire Mall Sioux Falls

    Check In15 00
    Check Out11 00

    Rated High
    • Upper-midscale, smoke-free hotel near Empire Mall
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - May 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 218 reviews  Read Recent Reviews

  • 1.9 miles Staybridge Suites Sioux Falls

    2505 South Carolyn Avenue, Sioux Falls, SD 57106
    1.9 miles from Sanford School of Medicine

    Enter Dates
    Staybridge Suites Sioux Falls

    Check In15 00
    Check Out11 00

    Rated High
    • Midscale, smoke-free, all-suite, extended-stay hotel
    • Near Empire Mall
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 271 reviews  Read Recent Reviews

  • 1.9 miles Hampton Inn Sioux Falls

    2417 South Carolyn Avenue, I-29, Exit 78, Sioux Falls, SD 57106
    1.9 miles from Sanford School of Medicine

    Enter Dates
    Hampton Inn Sioux Falls

    Check In15 00
    Check Out12 00

    Rated Very High
    • Upper-midscale, smoke-free hotel near Empire Mall
    • Also near I-29
    • Free shuttle to Sioux Falls Airport
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Free park and fly up to 7 nights only
    Not pet friendly - no pets allowed. - May 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 757 reviews  Read Recent Reviews

  • 2.0 miles Sheraton Hotel Sioux Falls

    1211 North West Avenue, Sioux Falls, SD 57104
    2.0 miles from Sanford School of Medicine

    Enter Dates
    Sheraton Hotel Sioux Falls

    Check In1500
    Check Out1200

    Rated Average
    • Upscale, smoke-free, full-service hotel
    • Connected to Sioux Falls Convention Center
    • Also near Sioux Falls Arena
    • Free 24-hour shuttle to Sioux Falls Airport
    • Heated indoor swimming pool - exercise room
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 518 reviews  Read Recent Reviews

  • 2.0 miles Ramada Hotel & Suites Sioux Falls Airport

    1301 West Russell, I-29, Exit 81, Sioux Falls, SD 57104
    2.0 miles from Sanford School of Medicine

    Enter Dates
    Ramada Hotel & Suites Sioux Falls Airport

    Check In16 00
    Check Out12 00

    Rated Average
    • Midscale, smoke-free, full-service hotel
    • Across highway from Sioux Falls Convention Center
    • Near arena - 1 mile south of Sioux Falls Airport
    • Free 24-hour shuttle to Sioux Falls Airport
    • Indoor waterpark - adult swimming pool
    • Exercise room
    • Free WiFi
    • Free parking
    • Free park and fly up to 7 nights only
    Not pet friendly - no pets allowed. - May 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 1308 reviews  Read Recent Reviews

  • 2.0 miles Candlewood Suites Sioux Falls

    2725 South Carolyn Avenue, Sioux Falls, SD 57106
    2.0 miles from Sanford School of Medicine

    Enter Dates
    Candlewood Suites Sioux Falls

    Check In15 00
    Check Out12 00

    Rated Very High
    • Midscale, smoke-free, all-suite, extended-stay hotel
    • Near Empire Mall
    • No swimming pool
    • Exercise room
    • Free WiFi
    • Free parking - truck parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 139 reviews  Read Recent Reviews

  • 2.0 miles Microtel Inn & Suites by Wyndham Sioux Falls

    2901 South Carolyn Avenue, Sioux Falls, SD 57106
    2.0 miles from Sanford School of Medicine

    Enter Dates
    Microtel Inn & Suites by Wyndham Sioux Falls

    Check In1500
    Check Out1100

    Rated Average
    • Cheap, smoke-free hotel near Empire Mall
    • No swimming pool
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 94 reviews  Read Recent Reviews

  • 2.1 miles TownePlace Suites by Marriott Sioux Falls

    4545 West Homefield Drive, I-29, Exit 78, Sioux Falls, SD 57106
    2.1 miles from Sanford School of Medicine

    Enter Dates
    TownePlace Suites by Marriott Sioux Falls

    Check In1500
    Check Out1100

    Rated High
    • Midscale, smoke-free, all-suite, extended-stay hotel
    • Near Empire Mall and I-29
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 186 reviews  Read Recent Reviews

  • 2.1 miles Best Western Empire Towers Inn Sioux Falls

    4100 West Shirley Place, I-29, Exit 77, Sioux Falls, SD 57106
    2.1 miles from Sanford School of Medicine

    Enter Dates
    Best Western Empire Towers Inn Sioux Falls

    Check In1500
    Check Out1100

    Rated Very High
    • Midscale, smoke-free hotel near Empire Mall
    • Also near I-29
    • Heated indoor swimming pool
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 605 reviews  Read Recent Reviews

  • 2.1 miles Comfort Suites Sioux Falls

    3208 South Carolyn Avenue, Sioux Falls, SD 57106
    2.1 miles from Sanford School of Medicine

    Enter Dates
    Comfort Suites Sioux Falls

    Check In15 00
    Check Out11 00

    Rated Average
    • Midscale, smoke-free, all-suite hotel near Empire Mall
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 207 reviews  Read Recent Reviews

  • 2.1 miles My Place Hotel Sioux Falls

    3005 South Carolyn Avenue, Sioux Falls, SD 57106
    2.1 miles from Sanford School of Medicine

    Enter Dates
    My Place Hotel Sioux Falls

    Check In15 00
    Check Out11 00

    Rated Very High
    • Midscale, smoke-free, all-suite, extended-stay hotel
    • No swimming pool
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 432 reviews  Read Recent Reviews

  • 2.1 miles Quality Inn & Suites South Sioux Falls

    3216 South Carolyn Avenue, Sioux Falls, SD 57106
    2.1 miles from Sanford School of Medicine

    Enter Dates
    Quality Inn & Suites South Sioux Falls

    Check In15 00
    Check Out11 00

    Rated Average
    • Midscale hotel near Empire Mall
    • Some smoking rooms
    • Heated indoor swimming pool
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 167 reviews  Read Recent Reviews

  • 2.1 miles Super 8 Hotel 41st Street Sioux Falls

    4100 West 41st Street, I-29, Exit 77, Sioux Falls, SD 57106
    2.1 miles from Sanford School of Medicine

    Enter Dates
    Super 8 Hotel 41st Street Sioux Falls

    Check In1500
    Check Out1100

    Rated Average
    • Cheap, smoke-free hotel near Empire Mall
    • Also near I-29
    • No swimming pool
    • Exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    Not pet friendly - no pets allowed. - May 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 696 reviews  Read Recent Reviews

  • 2.2 miles Courtyard by Marriott Hotel Sioux Falls

    4300 West Empire Place, I-29, Exit 77, Sioux Falls, SD 57106
    2.2 miles from Sanford School of Medicine

    Enter Dates
    Courtyard by Marriott Hotel Sioux Falls

    Check In1500
    Check Out1200

    Rated High
    • Upscale, smoke-free hotel near Empire Mall
    • Also near I-29
    • Free shuttle to Sioux Falls Airport
    • Heated indoor swimming pool - exercise room
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Feb 2015
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 163 reviews  Read Recent Reviews

  • 2.2 miles SpringHill Suites by Marriott Sioux Falls

    4304 West Empire Place, I-29, Exit 77, Sioux Falls, SD 57106
    2.2 miles from Sanford School of Medicine

    Enter Dates
    SpringHill Suites by Marriott Sioux Falls

    Check In1500
    Check Out1200

    Rated High
    • Midscale, smoke-free, all-suite hotel
    • Near Empire Mall and I-29
    • Free shuttle to Sioux Falls Airport
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    Not pet friendly - no pets allowed. - May 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 286 reviews  Read Recent Reviews

  • 2.2 miles Holiday Inn & Suites Airport Sioux Falls

    2040 West Russell Street, Sioux Falls, SD 57104
    2.2 miles from Sanford School of Medicine

    Enter Dates
    Holiday Inn & Suites Airport Sioux Falls

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free, full-service hotel
    • 3.5 miles from Sioux Falls Airport
    • Free shuttle to Sioux Falls Airport
    • Indoor swimming pool - exercise room
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 48 reviews  Read Recent Reviews

  • 2.3 miles Hyatt Place Hotel South Sioux Falls

    4935 West Lake Shore Blvd, Sioux Falls, SD 57106
    2.3 miles from Sanford School of Medicine

    Enter Dates
    Hyatt Place Hotel South Sioux Falls

    Check In15 00
    Check Out12 00

    Rated Very High
    • Upscale, smoke-free, full-service hotel near I-29, Exit 78
    • 2.5 miles from Empire Mall
    • Heated indoor swimming pool - exercise room
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 8 reviews  Read Recent Reviews

  • 2.3 miles Sleep Inn Sioux Falls

    1500 North Kiwanis Avenue, Sioux Falls, SD 57104
    2.3 miles from Sanford School of Medicine

    Enter Dates
    Sleep Inn Sioux Falls

    Check In14 00
    Check Out11 00

    Rated Average
    • Midscale, smoke-free hotel near convention center
    • 2 miles southwest of Sioux Falls Airport
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    Not pet friendly - no pets allowed. - Nov 2016
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 202 reviews  Read Recent Reviews

  • 2.3 miles Baymont Inn & Suites Sioux Falls

    3200 South Meadow Avenue, I-29, Exit 77, Sioux Falls, SD 57106
    2.3 miles from Sanford School of Medicine

    Enter Dates
    Baymont Inn & Suites Sioux Falls

    Check In1500
    Check Out1100

    Rated Average
    • Midscale, smoke-free hotel near Empire Mall
    • Also near I-29
    • Heated indoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 691 reviews  Read Recent Reviews

  • 2.4 miles La Quinta Inn & Suites Sioux Falls

    4521 West 41st Street, I-29, Exit 77, Sioux Falls, SD 57106
    2.4 miles from Sanford School of Medicine

    Enter Dates
    La Quinta Inn & Suites Sioux Falls

    Check In15 00
    Check Out11 00

    Rated Very High
    • Midscale, smoke-free hotel near Empire Mall
    • Also near I-29
    • Heated indoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 738 reviews  Read Recent Reviews

  • 2.4 miles Days Inn Sioux Falls

    3401 Gateway Blvd, I-29, Exit 77, Sioux Falls, SD 57106
    2.4 miles from Sanford School of Medicine

    Enter Dates
    Days Inn Sioux Falls

    Check In1500
    Check Out1200

    Rated Average
    • Cheap, smoke-free hotel
    • Near Empire Mall and I-29
    • No swimming pool
    • Exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 598 reviews  Read Recent Reviews

  • 2.4 miles Econo Lodge Sioux Falls

    3500 Gateway Blvd, I-29, Exit 77, Sioux Falls, SD 57106
    2.4 miles from Sanford School of Medicine

    Enter Dates
    Econo Lodge Sioux Falls

    Check In15 00
    Check Out11 00

    Rated Average
    • Cheap, smoke-free, interstate hotel near Empire Mall
    • Also near I-29
    • No swimming pool
    • Exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    Pet friendly hotel More >
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 463 reviews  Read Recent Reviews

  • 2.4 miles AmericInn Hotel & Suites Sioux Falls

    3508 South Gateway Blvd, I-29, Exit 77, Sioux Falls, SD 57106
    2.4 miles from Sanford School of Medicine

    Enter Dates
    AmericInn Hotel & Suites Sioux Falls

    Check In1500
    Check Out1100

    Rated High
    • Midscale, smoke-free hotel near Empire Mall
    • Also near I-29
    • Heated indoor swimming pool
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    Not pet friendly - no pets allowed. - Jan 2017
    Most Recent HotelGuides Reviews Read >
    TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 335 reviews  Read Recent Reviews

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Sioux Falls Info

University of South Dakota
Sanford School of Medicine




Nearby Attractions


Hotels near Sanford USD Medical Center   0.2 mile north
Hotels near Sanford Children's Hospital   0.2 mile NW
Hotels near University of Sioux Falls   0.3 mile SE
Hotels near Sioux Falls VA Medical Center   0.6 mile west
Hotels near Augustana University   0.8 mile south
Hotels near Great Plains Zoo and Delbridge Museum   1.0 mile west
Hotels near Washington Pavilion   1.1 miles NE
Hotels near Downtown Sioux Falls   1.3 miles NE
Hotels near Avera McKennan Hospital   1.4 miles east
Hotels near Orpheum Theater Sioux Falls   1.4 miles NE
Hotels near Sioux Falls Specialty Hospital   1.4 miles east
Hotels near WH Lyon Fairgrounds   1.9 miles NW
Hotels near Denny Sanford Premier Center   1.9 miles north
Hotels near Falls Park   1.9 miles NE
Hotels near Yankton Trail Park   2.0 miles south

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How Do We Order Hotels?

We order the hotels on this page by how close they are to this attraction.

Most of our competitors order these same hotels in other ways that make them more money.
How Do We Define Motel?

To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.

At hotels, on the other hand, you can enter your room only through a hall inside the building.
Sioux Falls Hotel Tips

Important Hotel Tips




Address: 1400 West 22nd Street, Sioux Falls, SD 57105 Hotels, Motels, Lodging, and Accommodations near University of South Dakota School of Medicine, South Dakota Medical School, Sioux Falls, South Dakota, USA

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