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Cairo, IL Hotels & Motels | HotelGuides.com
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Hotels > US Hotels > Hotels in Illinois > Cairo Hotels & Motels

Hotels and Motels in or near Cairo, IL


 
  • Quality Inn Cairo - I-57, Exit 1
    13201 Kessler Road, I-57, Exit 1, Cairo, IL 62914 Call Us

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    Dates
    Quality Inn Cairo - I-57, Exit 1

    Check In16 00
    Check Out11 00

    Rated Average
    • Midscale, interstate motel northwest of downtown
    • Near I-57 at US 51
    • 2 floors, 38 rooms - no elevator
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 68 reviews 
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  • Eagle Inn Charleston - I-57, Exit 12
    2811 East Marshall Street, I-57, Exit 12, Charleston, MO 63834 Call Us 9 miles
    9 miles from Cairo

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    Dates
    Eagle Inn Charleston - I-57, Exit 12

    Check In16 00
    Check Out11 00

    Rated Average
    • Cheap, highway motel near I-57 at US 62
    • 2.5 miles east of downtown Charleston
    • Single-story, 20 rooms
    • Some smoking rooms
    • No swimming pool
    • Microwave and refrigerator in every room
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 22 reviews 
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  • Super 8 Motel Charleston - I-57, Exit 12
    310 South Story Street, Building A, I-57, Exit 12, Charleston, MO 63834 Call Us 10 miles
    10 miles from Cairo

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    Dates
    Super 8 Motel Charleston - I-57, Exit 12

    Check In1500
    Check Out1100

    Rated Average
    • Cheap motel near I-57 at US 62
    • This motel is located 1.5 miles east of downtown Charleston.
    • Single-story, 60 rooms
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 268 reviews 
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  • Quality Inn Charleston - I-57, Exit 10
    102 Drake Street, I-57, Exit 10, Charleston, MO 63834 Call Us 12 miles
    12 miles from Cairo

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    Dates
    Quality Inn Charleston - I-57, Exit 10

    Check In15 00
    Check Out11 00

    Rated Average
    • Midscale motel near I-57 at MO 105
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 77 reviews 
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  • Americas Best Value Inn Ullin - I-57, Exit 18
    128 Cheekwood Lane, I-57, Exit 18, Ullin, IL 62992 Call Us 18 miles
    18 miles from Cairo

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    Dates
    Americas Best Value Inn Ullin - I-57, Exit 18

    Check In15 00
    Check Out11 00

    Rated High
    • Cheap hotel near I-57, Exit 18
    • 2 miles from downtown Ullin
    • 2 floors, 40 rooms - no elevator
    • Some smoking rooms
    • Heated indoor swimming pool open in summer
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 86 reviews 
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    More Reviews

  • Best Western Plus Sikeston Hotel
    120 South Interstate Drive, Sikeston, MO 63801 Call Us 21 miles
    21 miles from Cairo

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    Dates
    Best Western Plus Sikeston Hotel

    Check In1500
    Check Out1100

    Rated Average
    • Upper-midscale, smoke-free hotel near US 62 at I-55
    • Near Sikeston Factory Outlet Mall
    • 2 floors, 55 rooms - elevator
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 466 reviews 
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  • Days Inn & Suites Sikeston - I-55, Exit 67
    220 South Interstate Drive, I-55, Exit 67, Sikeston, MO 63801 Call Us 21 miles
    21 miles from Cairo

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    Dates
    Days Inn & Suites Sikeston - I-55, Exit 67

    Check In15 00
    Check Out11 00

    Rated Average
    • Cheap hotel near I-55 at Hwy 62
    • 4 miles from Sikeston Jaycee Bootheel Rodeo
    • 2 floors, 60 rooms and suites - elevator
    • Some smoking rooms
    • Outdoor swimming pool open in summer Exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 220 reviews 
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  • Drury Inn & Suites Sikeston - I-55, Exit 67
    2608 East Malone, I-55, Exit 67, Sikeston, MO 63801 Call Us 21 miles
    21 miles from Cairo

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    Dates
    Drury Inn & Suites Sikeston - I-55, Exit 67

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free hotel near I-55
    • Also near Sikeston Factory Outlet Mall
    • 5 floors, 154 rooms and suites
    • Heated indoor-outdoor swimming pool - exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 477 reviews 
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  • Super 8 Hotel Miner Area Sikeston - I-55, Exit 67
    2609 East Malone, I-55, Exit 67, Sikeston, MO 63801 Call Us 21 miles
    21 miles from Cairo

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    Dates
    Super 8 Hotel Miner Area Sikeston - I-55, Exit 67

    Check In15 00
    Check Out11 00

    Rated Average
    • Cheap hotel near Sikeston Factory Outlet Mall
    • Also near I-55, Exit 67
    • 2 floors, 63 rooms and suites - no elevator
    • Some smoking rooms
    • No swimming pool
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 372 reviews 
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  • Comfort Inn & Suites Sikeston - I-55, Exit 67
    109 Matthews Lane, I-55, Exit 67, Sikeston, MO 63801 Call Us 21 miles
    21 miles from Cairo

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    Dates
    Comfort Inn & Suites Sikeston - I-55, Exit 67

    Check In14 00
    Check Out11 00

    Rated Average
    • Midscale, smoke-free hotel near I-55
    • Also near Sikeston Factory Outlet Mall
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 136 reviews 
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    More Reviews

  • Holiday Inn Express & Suites Sikeston
    115 Hospitality Drive, Sikeston, MO 63801 Call Us 25 miles
    25 miles from Cairo

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    Dates
    Holiday Inn Express & Suites Sikeston

    Check In15 00
    Check Out11 00

    Rated High
    • Upper-midscale, smoke-free hotel near US 62 at US 60
    • 3 floors, 73 rooms and suites - elevator
    • Heated indoor swimming pool - exercise room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 121 reviews 
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  • Hampton Inn Sikeston
    1240 Commerce Drive, Sikeston, MO 63801 Call Us 25 miles
    25 miles from Cairo

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    Dates
    Hampton Inn Sikeston

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free hotel near downtown
    • Also near US 61 at US 60
    • 4 floors, 92 rooms
    • Heated indoor swimming pool
    • 24-hour exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 111 reviews 
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    More Reviews

  • Baymont Inn & Suites Metropolis
    203 East Front Street, Metropolis, IL 62960 Call Us 26 miles
    26 miles from Cairo

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    Dates
    Baymont Inn & Suites Metropolis

    Check In15 00
    Check Out11 00

    Rated Average
    • Midscale, smoke-free, downtown Metropolis hotel
    • Near Harrah's Casino - 2 miles from Fort Massac State Park
    • 2 floors, 118 rooms and suites - no elevator
    • Heated indoor swimming pool - exercise room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 671 reviews 
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  • Baymont Inn & Suites Paducah - I-24, Exit 3
    5300 Cairo Road, I-24, Exit 3, Paducah, KY 42001 Call Us 28 miles
    28 miles from Cairo

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    Dates
    Baymont Inn & Suites Paducah - I-24, Exit 3

    Check In15 00
    Check Out12 00

    Rated Average
    • Midscale hotel near Kentucky Oaks Mall and I-24
    • 3 floors, 72 rooms and suites - elevator
    • Some smoking rooms
    • No swimming pool
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  3.0 of 5 stars
    Based on 469 reviews 
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  • Quality Suites Paducah - I-24, Exit 4
    2880 James Sanders Blvd, I-24, Exit 4, Paducah, KY 42001 Call Us 28 miles
    28 miles from Cairo

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    Dates
    Quality Suites Paducah - I-24, Exit 4

    Check In15 00
    Check Out11 00

    Rated Average
    • Midscale, smoke-free, all-suite hotel
    • Near US 60 and I-24
    • 2 floors, 60 studio suites - no elevator
    • Heated indoor swimming pool - exercise room
    • Microwave and refrigerator in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 332 reviews 
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    More Reviews

  • Country Inn & Suites by Radisson Paducah - I-24, Exit 4
    145 McBride Lane, I-24, Exit 4, Paducah, KY 42001 Call Us 28 miles
    28 miles from Cairo

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    Dates
    Country Inn & Suites by Radisson Paducah - I-24, Exit 4

    Check In15 00
    Check Out11 00

    Rated Average
    • Upper-midscale, smoke-free hotel near I-24 at US 60
    • Also near Kentucky Oaks Mall
    • 3 floors, 61 rooms and suites - elevator
    • Indoor swimming pool - exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 685 reviews 
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  • Super 8 Motel West Paducah - I-24, Exit 4
    5001 Hinkleville Road, I-24, Exit 4, Paducah, KY 42001 Call Us 28 miles
    28 miles from Cairo

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    Dates
    Super 8 Motel West Paducah - I-24, Exit 4

    Check In1400
    Check Out1100

    Rated Average
    • Cheap motel near US 60 at I-24
    • Also near Kentucky Oaks Mall
    • 2 floors, 37 rooms - no elevator
    • Some smoking rooms
    • No swimming pool
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 444 reviews 
    Read Recent Reviews
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  • Drury Inn & Suites Paducah - I-24, Exit 4
    2930 James Sanders Blvd, I-24, Exit 4, Paducah, KY 42001 Call Us 28 miles
    28 miles from Cairo

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    Dates
    Drury Inn & Suites Paducah - I-24, Exit 4

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free hotel near US 60 at I-24
    • 6 floors, 141 rooms and suites
    • Heated indoor swimming pool - exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 497 reviews 
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    More Reviews

  • Candlewood Suites Paducah - I-24, Exit 4
    3940 Coleman Crossing Circle, I-24, Exit 4, Paducah, KY 42001 Call Us 28 miles
    28 miles from Cairo

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    Dates
    Candlewood Suites Paducah - I-24, Exit 4

    Check In15 00
    Check Out12 00

    Rated Average
    • Midscale, smoke-free, all-suite, extended-stay hotel
    • Near Kentucky Oaks Mall and I-24
    • 4 floors, 85 suites
    • No swimming pool
    • 24-hour exercise room
    • Kitchen in every suite
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 150 reviews 
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  • Comfort Suites Paducah - I-24, Exit 4
    3918 Coleman Crossing Circle, I-24, Exit 4, Paducah, KY 42001 Call Us 28 miles
    28 miles from Cairo

    Enter
    Dates
    Comfort Suites Paducah - I-24, Exit 4

    Check In15 00
    Check Out11 00

    Rated Very High
    • Midscale, smoke-free, all-suite hotel
    • Near Kentucky Oaks Mall
    • 4 floors, 72 suites
    • Heated indoor swimming pool - exercise room
    • Microwave and refrigerator in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Not pet friendly

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Cairo Info

Pet Friendly Hotels in or near Cairo

Cairo Group Hotel Rates

Hotels near Me

Nearby Attractions


Hotels near Mound City National Cemetery   6 miles north
Hotels near Lambert's Cafe   22 miles west
Hotels near Harrah's Metropolis Casino   26 miles NE
Hotels near Purple Toad Winery   28 miles east
Hotels near Century Casino Cape Girardeau   28 miles NW
Hotels near Southeast Missouri State University   29 miles NW

Nearby Cities


Scott City MO Hotels   24 miles NW
Sikeston MO Hotels   24 miles west
Metropolis IL Hotels   28 miles east
How Do We Order Hotels?

On place pages like this, we order hotels from lowest cost to highest – except we list low-rated hotels at the bottom of the page.

Most of our competitors order these same hotels in other ways that make them more money.
How Do We Define Motel?

To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.

At hotels, on the other hand, you can enter your room only through a hall inside the building.
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Hotel Booking Tips
  1. Beware of non-refundable reservations that could cost you a lot of money if you change or cancel them. +Non-refundable reservations are a gamble that will usually save you less than $10. If you make a $90 non-refundable reservation instead of a $100 refundable booking, you are betting $90 to win $10. Would you do that in Las Vegas?
  2. Don't assume you can cancel a non-refundable reservation without penalty if you notify the hotel weeks or even months in advance. +Often you cannot – because some hotels' profit strategy is to get paid more than once for the same room for the same night.
  3. Always read cancellation policies carefully before you make a reservation. + When is the latest date and time you can cancel without penalty?
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  4. When you make a reservation, you will receive a confirmation email. Take a copy with you to the hotel.
  5. The earlier in the afternoon you check into a hotel, the more likely you will get a room or suite that matches your preferences.



Cairo Hotels, Motels, Lodging, and Accommodations – Cairo, Illinois IL Ill, USA

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