Midscale, smoke-free hotel near I-95 at US 301
3 floors, 81 rooms and suites - elevator
Outdoor swimming pool open in summer - exercise room
Microwave and refrigerator in every room
Free hot breakfast buffet
Free Internet in room
"Great place to stay on I-95. Our requested 1st floor room was clean and had nice furnishings. The temperature was cool and comfortable. A courteous hotel clerk greeted us at check-in with the good news that our room was ready. Good cookies, and breakfast was excellent.2015-05-18"
"The continental breakfast attendant went out of her way to make sure guests had everything they needed. I've stayed at this hotel before, and she always brightens up the day. Eat at Captain's Quarters across the street while you're here. Nice stay. 2015-03-23"
"Good value - room was large for a family of 4 - had free Internet access - continental breakfast provided.2011-07-01"
"Convenient to I-95 and restaurants - good staff.2011-03-01"
"Easy to find and near plenty of restaurants - room was nice, clean, and comfortable - I'd stay again.2007-12-01"
"Large, clean room - loved the bed and whirlpool tub - kitchen area had a few ants - wonderful place to stay.2007-05-01"
Photos of Hampton Inn Santee
Map of Hampton Inn Santee
Attractions near Hampton Inn Santee with estimated distances
Oliver Dawson Stadium - 22 miles west
South Carolina State University - 22 miles west
Claflin University - 23 miles west
Edisto Memorial Gardens - 24 miles west
World Grits Festival - 25 miles south
Select check-in date
Select check-out date
Why Book Here?
Lowest price guarantee
Pay at hotel in most cases
If you don't like your hotel, we'll refund your money.